The Alzheimer's Association is proud to celebrate the individuals who have made significant contributions to further the vision of a world without Alzheimer's disease.
AAIC provides the Alzheimer's Association with the opportunity to present awards to some of the most prominent leaders in the field. These prestigious awards recognize the work of distinguished Alzheimer's researchers, as well as those who are just beginning their career in this vital field.
The AAIC Lifetime Achievement Awards recognize a senior investigator whose contributions, whether they have been in research, leadership or mentorship, have shown a lasting impact on the field and whose body of work has demonstrated a lifetime commitment towards progress against Alzheimer's and dementia.
The awards are named in honor of Henry Wisniewski, M.D., Ph.D.; Khalid Iqbal, Ph.D.; and Bengt Winblad, M.D., Ph.D.—co-founders of the Alzheimer's Association scientific conference, now known as the Alzheimer's Association International Conference (AAIC). Since its inception and first iteration they each held key leadership roles in planning and conceptualizing the conference:
Dr. Koo is Professor of Medicine and Physiology at the National University of Singapore Yong Loo Lin School of Medicine and the Department of Neurosciences at the University of California, San Diego School of Medicine. Dr. Koo is recognized for his contributions in furthering understanding of the molecular and cellular pathophysiology of Alzheimer’s disease. Dr. Koo is recognized for his studies on characterizing the pathways of production of the amyloid beta-protein from the amyloid precursor protein (APP) as well as the physiological and pathological functions of APP. His work has also contributed to Alzheimer’s therapeutics. More recently, he has focused his attention on how synapses are damaged in Alzheimer’s disease.
Dr. Kawas is the Al and Trish Nichols Chair in Clinical Neuroscience and Professor of Neurology and Neurobiology & Behavior at the University of California, Irvine. Dr. Kawas is recognized for her numerous contributions to clinical and epidemiological research in Alzheimer’s disease, aging and dementia. Over the past 30 years, Dr. Kawas has conducted clinical trials, clinical pathological correlations and investigations of risk and protective factors for dementia in numerous longitudinal studies, including the Bronx Aging Study, the Baltimore Longitudinal Study of Aging (National Institute on Aging), and most recently, The 90+ Study, a population based sample of more than 1,800 people aged 90 years and older. As co-principal investigator of the 90+ Study, Dr. Kawas has examined what allows people to live to age 90 and beyond, and the factors associated with dementia and cognitive resilience at this age. A major finding from the study is that about a quarter of the people with dementia over age 90 do not have sufficient Alzheimer’s disease or other neuropathologic changes in their brain to explain their cognitive loss, while 40% of individuals without dementia have high levels of Alzheimer’s disease pathology and appear resilient to its deleterious effects.
Dr. Hugh Hendrie is Professor Emeritus, Department of Psychiatry, Indiana University School of Medicine; Distinguished Scientist, Regenstrief Institute, Inc.; Center Scientist, Indiana University Center for Aging Research. Dr. Hendrie is recognized for his many contributions in furthering understanding of dementia and its risk factors, particularly as they apply to diverse populations. He served as a principle investigator for the largest and longest National Institute on Aging (NIA)-funded study of its kind – the Indianapolis-Ibadan Dementia Project. This study was one of the first to identify the link between cardiovascular risk factors and dementia as well as demonstrating differences in incidence rates and genetic risk factors between the populations. Dr. Hendrie was a member of an early initiative by NIA and the World Health Organization to encourage international studies in dementia. He continues to collaborate on international studies of dementia and clinical intervention trials for the treatment of dementia.
The Jerome H. Stone Philanthropy Award for Alzheimer's Research honors the legacy of Mr. Jerome Stone, a visionary who was among the first to call for investment in Alzheimer's research. Inspired by the loving memory of his late wife, Evelyn T. Stone, he took the helm of the Alzheimer's movement as the primary founder of the Alzheimer's Association.
Mr. Stone was renowned for his leadership, determination and generosity in the fight against Alzheimer’s, and for his support of research in particular. For many years, he served as the honorary chair of the Alzheimer's Association National Board of Directors. Mr. Stone passed away on January 1, 2015 at the age of 101.
This award, given in his name, honors the world's top philanthropists for advancing scientific progress toward treatment and prevention of Alzheimer's disease through their generous commitment to research.
Michaela “Mikey” Hoag, of Atherton, CA, is recognized for her philanthropic contributions in support of Alzheimer’s research, most notably the highly successful Part the Cloud initiative she launched in 2012. This novel initiative funds earlier stage clinical studies to help accelerate the transition of findings from the laboratory into possible therapies. Part the Cloud bridges an important gap by supporting promising research ideas that often stall due to lack of funding.
The Inge Grundke-Iqbal Award for Alzheimer's Research is presented to the senior author of the most impactful study published in Alzheimer's research over the preceding two years.
Only members from the International Society to Advance Alzheimer’s Research and Treatment (ISTAART) may nominate candidates. Please consider potential candidates to nominate for this exciting award.
Dr. Ben Barres received the Inge Grundke-Iqbal Award for research advancing the understanding of the novel role the apolipoprotein E (APOE) gene plays in controlling the rate of synapse pruning and turnover in the brain by astrocytes. Specifically, his research found that APOE-e2 enhances the rate of synapse pruning and turnover in the brain while APOE-e4 decreases it. Dr. Barres and his team further reported that APOE alleles control the rate of accumulation of the complement C1q protein, with APOE-e4 leading to a glut of this protein in the brains of laboratory mice. Dr. Barres is former chair of the Department of Neurobiology at Stanford University and creator and director of the Masters of Science in Medicine Program, an intensive program at Stanford University to train Ph.D. students about human biology and disease.
About Dr. Inge Grundke-Iqbal
Inge Grundke-Iqbal served as Professor and Head of Neuroimmunology at the New York State Institute for Basic Research in Developmental Disabilities from 1977 until her passing in September 2012. She was a world renowned neuroscientist and Alzheimer disease researcher. She was author/co-author of over 250 scientific publications in prestigious American and international journals and books. Dr. Grundke-Iqbal made several seminal discoveries in the biology of Alzheimer's disease and related conditions. Her discovery of the abnormal hyperphosphorylation of tau opened a whole new area of research in neurodegeneration, especially Alzheimer's disease and related tauopathies. Her research contributions won her several U.S. Public Health Service, National Institutes of Health and non-federal research grants and honors. Dr. Grundke-Iqbal served as a member of the International Scientific Advisory Committee of the International Conference on Alzheimer's Disease and Related Disorders (now known as the Alzheimer's Association International Conference).
The de Leon Prizes in Neuroimaging recognize a senior scientist and a new investigator (first authors) who are judged to have each published the best paper in any peer-reviewed journal related to the topic of in-vivo neuroimaging of a neurodegenerative process. Members of the ISTAART Neuroimaging Professional Interest Area (NPIA) are the nominating body for the two awards.
Dr. Johnson is a Professor of Radiology and Neurology at the Harvard Medical School, Radiologist and Director of Molecular Neuroimaging at Massachusetts General Hospital (MGH), Associate physician and staff neurologist in the Memory Disorders Unit at the Brigham and Women's Hospital, as well as a Clinical Associate in Neurology at the MGH. He co-directs the Harvard Aging Brain Study and Neuro-imaging Core of the Massachusetts Alzheimer’s Disease Research Center, and is the founding Organizer of the Human Amyloid Imaging meeting. Dr. Johnson is recognized for his paper titled, “Tau Positron Emission Tomographic Imaging in Aging and Early Alzheimer Disease,” which was published in the American Neurological Association.
Dr. Ossenkoppele is Assistant Professor at the Alzheimer Center of the VU University Medical Center in Amsterdam. The award-winning paper was published during his postdoctoral fellowship at the Memory and Aging Center of the University of California San Francisco, with Professor Gil Rabinovici and Professor William Jagust.
Named in honor of noted scientist, administrator, consultant, lecturer and author, Zaven Khachaturian, Ph.D., this award recognizes an individual whose compelling vision, selfless dedication, and extraordinary achievement has significantly advanced the field of Alzheimer science. Dr. Khachaturian currently is editor-in-chief of Alzheimer’s & Dementia: The Journal of the Alzheimer's Association. He is universally recognized as the chief architect of Alzheimer's research in the United States. Prior to leaving federal service, he served as the Director of the Office of Alzheimer’s Disease Research and coordinated all Alzheimer’s disease-related activities at the National Institutes of Health (NIH).
Dr. Klunk is recognized for his many contributions to Alzheimer’s research, including his influential work in regard to amyloid imaging. His group’s initial work on amyloid imaging in humans was cited in Discover Magazine’s “100 Top Science Stories of 2002,” and their benchmark 2004 paper in amyloid imaging was awarded the “Best Neuroimaging Paper from 2002-2004” by the Alzheimer’s Association and was cited by Nature Medicine as #1 among “key papers in the field” of Alzheimer’s disease research from 2003-2006. It remains the most frequently cited research article in the field of Alzheimer’s disease neuroimaging since its publication in 2004.
Dr. Klunk is a Distinguished Professor of Psychiatry and Neurology and the Levidow-Pittsburgh Foundation Chair in Alzheimer’s Disease and Dementia Disorders at the University of Pittsburgh School of Medicine in Pittsburgh, PA. He is also the Co-Director of the Alzheimer’s Disease Research Center at the University of Pittsburgh, and the director of the Laboratory of Molecular Neuropharmacology at Western Psychiatric Institute and Clinic. He served on the Medical and Scientific Advisory Council of the Alzheimer’s Association from 2005 to the present where he is immediate Past Chair of the MSAC.
Using review scores as a guide, the AIC Chairs judge and select the best oral and poster presentations presented during AIC. The 2017 recipients will be announced onsite during AIC 2017.
Competitions are held in each conference program theme to determine the best posters by students and post-docs at AAIC. Judging will take place onsite by the Scientific Program Committee and invited guest judges. The competition is based on the four programmatic themes of AAIC: Basic and Translational Science, Diagnosis and Prognosis, Public Health and Psychosocial, and Therapeutics. Students and post-docs may submit their interest in the poster competition during abstract submission.
Basic and Translational Science Theme Recipient: Lindsay Welikovitch
Poster: Identifying the Neuronal Aβ-Immunopositive Pool within the Human Hippocampus
Diagnosis and Prognosis Theme Recipient: Merle Hönig
University Hospital Cologne
Poster: Tau Pathology Burden Associated with Level of Cognitive Reserve in Alzheimer’s Disease
Public Health and Psychosocial Theme Recipient: Andrew Sommerlad
University College London
Poster: SF-DEM: A New Instrument for Assessing Social Functioning in Dementia
Therapeutics Theme Recipient: Anna Rosenberg
University of Eastern Finland
Poster: Multidomain Lifestyle Intervention Benefits a Large Elderly Population at Risk for Cognitive Decline: Subgroup Analyses of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Basic and Translational Science Theme Recipient: Lindsay Hohsfield
University of California, Irvine
Poster: Characterizing the Effects of Microglial Elimination and Repopulation on Abeta and Tau Pathology
Diagnosis and Prognosis Theme Recipient: Renaud La Joie
University of California, San Francisco
Poster: Does APOE ε4 Have an Aβ-Independent Effect on Tau Pathology? Neuroimaging Investigations in Cognitively Normal Elders and Patients with Alzheimer’s Diseas
Public Health and Psychosocial Theme Recipient: Claire McEvoy
University of California, San Francisco
Poster: Dietary Inflammatory Index, Inflammation and Cognitive Decline in Older Adults: The Health ABC Study
Therapeutics Theme Recipient: Rachel Wong
University of Newcastle
Poster: Cerebrovascular Function, Cognition and Overall Well-Being in Postmenopausal Women Are Improved Following Regular Resveratrol Supplementation
Congratulations to the recipients of the 2017 AAIC Memorial Travel Fellowships. The 2017 fellowships are in memory of the following notable leaders in the field:
Hyemin Jang, Samsung Medical Center, South Korea
Synergistic Effect of Tau, Amyloid, and Vascular Burden on Cognitive Decline in Patients with Subcortical Vascular Cognitive Impairments
Silvan Licher, Erasmus MC University Medical Center Rotterdam, Netherlands
External Validation of Five Models for Predicting Dementia in the General Community-Dwelling Population: Results from the Prospective Population-Based Rotterdam Study
Thais Machado, Universidade Federal de Minas Gerais, Brazil
Short-TERM Rehabilitation for Linguistic Impairments in Primary Progressive Aphasia - A Case Series
Don't miss this innovative aspect of the AAIC program highlighting basic dementia science.