Alzheimer's Imaging Consortium, an AAIC preconference
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Alzheimer's Imaging Consortium

Saturday, July 23, 2016
8 a.m. – 5:30 p.m.
Metro Toronto Convention Centre

Toronto, Canada

Overview
AIC registration fellowships
Program chairs
Plenary speakers
Agenda
Target audience
Registration
About ISTAART

Overview

The Alzheimer's Imaging Consortium (AIC), a preconference to the Alzheimer's Association International Conference (AAIC), will focus on the clinical application and methodological development of neuroimaging (MRI, PET, SPECT, CT and others) to Alzheimer's disease, other dementias and normal brain aging. The program consists of invited speakers, as well as oral and poster presentations from submitted abstracts.

AIC is organized by the Neuroimaging Professional Interest Area of the International Society to Advance Alzheimer's Research and Treatment (ISTAART).

AIC registration fellowships (The application process is closed.)

A limited number of fellowships, in the form of complimentary AIC registration, are available for early career scientists who are the presenting author on an accepted abstract.

Program chairs

Plenary speakers

Brad Dickerson

MGH/Harvard Medical School, Boston, Mass., United States

Clifford Jack

Mayo Clinic, Rochester, Minn., United States

Renaud La Joie

Memory and Aging Center, University of California, San Francisco, San Francisco, Calif., United States;
Inserm, Université de Caen Normandy U1077, Caen, France

Christian Sorg

University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Agenda

8 – 8:30 a.m.

Opening Remarks

8:30 – 9 a.m.

Plenary Session: What Have We Learned?
Renaud La Joie
, Memory and Aging Center, University of California, San Francisco, San Francisco, Calif., United States;
Inserm, Université de Caen Normandy U1077, Caen, France

9:00 – 10:15 a.m.

IC-01 Tau Imaging
Chairs: Liana Apostolova, Indiana University School of Medicine, Indianapolis, IN, USA; Indiana Alzheimer Disease Center, Indianapolis, IN, USA; University of California, Los Angeles, Los Angeles, CA, USA
Victor Villemagne, AIBL Research Group, Perth and Melbourne, Australia; The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia; Department of Molecular Imaging and Therapy, Centre for PET, Austin Health, Heidelberg, Australia

IC-01-01 Predictors of Regional Tau-PET Uptake: Mayo Clinic Study of Aging
Prashanthi Vemuri, Val Lowe, Heather Wiste, Stephen Weigand, Matthew Senjem, David Knopman, Ronald Petersen, Clifford Jack

IC-01-02 The Association Between Aβ and Tau Accumulations and Its Influence on Clinical Features in Aging and Alzheimer’s Disease Spectrum Brains: [11c] PBB3 PET Study
Hitoshi Shimada, Tetsuya Suhara, Hitoshi Shinotoh, Hironobu Endo, Fumitoshi Niwa, Soichiro Kitamura, Shigeki Hirano, Yasuyuki Kimura, Makiko Yamada, Naruhiko Sahara, Ming-Rong Zhang, Satoshi Kuwabara, Makoto Higuchi

IC-01-03 Classifying Tau PET Positivity with [18F]-AV-1451 in Preclinical Alzheimer's Disease
Shruti Mishra, Brian Gordon, Karl Friedrichsen, Yi Su, Jon Christensen, Patricia Aldea, Nigel Cairns, John Morris, Beau Ances, Tammie Benzinger

IC-01-04 18f-AV1451 PET Detects Tau Pathology in Mapt Mutation Carriers and Correlates Strongly with Immunohistochemistry of Tau Aggregates
Ruben Smith, Andreas Puschmann, Tomas Olsson, Elisabet Englund, Oskar Hansson

IC-01-05 Neuropathologic Features of AV1451 Tau PET Autoradiography in Dementia
Melissa Murray, Geoffry Curran, Ping Fang, Keith Josephs, Joseph Parisi, Kejal Kantarci, Bradley Boeve, Mukesh Pandey, Tyler Bruinsma, David Knopman, David Jones, Leonard Petrucelli, Casey Cook, Dennis Dickson, Ronald Petersen, Clifford Jack, Val Lowe

10:15 – 10:30 a.m.

Break

10:30 – 11 a.m.

Plenary Session: Alzheimer’s Disease Imaging Biomarkers and Aging
Clifford Jack
, Mayo Clinic, Rochester, Minn., United States

11 a.m. – 12:15 p.m.

IC-02 Imaging Genetics
Chairs:
Elizabeth Mormino
, Massachusetts General Hospital, Charlestown, MA, USA
Frederik Barkhof, Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands; Neuroscience Campus Amsterdam, Amsterdam, Netherlands; University College London, London, United Kingdom

IC-02-01 The Effects of the Top 20 Alzheimer’s Disease Risk Genes on Brain Atrophy
Tugce Duran, Shannon Risacher, Naira Goukasian, Triet Do, John West, Kwangsik Nho, Jonathan Grotts, David Elashoff, Andy Saykin, Liana Apostolova

IC-02-02 Genome-Wide Polygenic Risk for Alzheimer’s Disease Is Associated with Rate of Metabolic Decline but Not with Rate of Amyloid Deposition
Andre Altmann, Marc Modat, Sebastien Ourselin

IC-02-03 Linking Gene Pathways and Brain Atrophy in Alzheimer's Disease
Marco Lorenzi, Boris Gutman, Andre Altmann, Derrek Hibar, Neda Jahanshad, Daniel Alexander, Paul Thompson, Sebastien Ourselin

IC-02-04 Correlation of Cortical Thickness in Cognitively Healthy Elderly Monozygotic Twin Pairs
Anouk den Braber, Elles Konijnenberg, Mara ten Kate, Betty Tijms, Frederik Barkhof, Dorret Boomsma, Philip Scheltens, Pieter Jelle Visser

IC-02-05 Cerebrospinal Fluid sTREM2 Levels Are Associated with Gray Matter Volume Increases and Reduced Diffusivity in Early Alzheimer’s Disease
Juan Gispert, Marc Suarez-Calvet, Gemma Monte, Alan Tucholka, Carles Falcon, Santiago Rojas, Lorena Rami, Raquel Sanchez-Valle, Albert Llado, Gernot Kleinberger, Christian Haass, Jose Luis Molinuevo

12:15 – 2 p.m.

Lunch and poster viewing/poster judging

2 – 3 p.m.

Controversy Debate: Alzheimer's Disease – Single vs. Multiple Brain Network Disorder
Moderator: David Wolk, University of Pennsylvania School of Medicine, Philadelphia, Pa., United States

Controversy Debate: Single Brain Network Disorder
Christian Sorg, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Controversy Debate: Multiple Brain Network Disorder
Brad Dickerson, MGH/Harvard Medical School, Boston, Mass., United States

3 – 3:15 p.m.

Break

3:15 – 4:30p.m.

IC-03 Brain Networks and Connectomics
Chairs:
David Wolk
, University of Pennsylvania, Philadelphia, PA, USA Ann Cohen, University of Pittsburgh, Pittsburgh, PA, USA

IC-03-01 Regional Gray Matter Volume and Default Mode Network Connectivity Are Associated with Age Relative to Parental Symptom Onset in Sporadic Alzheimer’s Disease
Jacob Vogel, Pierre Orban, Alexa Pichet Binette, Renaud La Joie, Melissa Savard, Angela Tam, John Breitner, Pierre Bellec, Sylvia Villeneuve

IC-03-02 Grey Matter Connectivity Is Associated with Clinical Progression in Non-Demented, Amyloid Positive Patients.
Betty Tijms, Mara ten Kate, Sander Verfaillie, Alida Gouw, Charlotte Teunissen, Frederik Barkhof, Philip Scheltens, Wiesje van der Flier

IC-03-03 Cognitive Complaints in Older Adults at Risk for Alzheimer’s Disease Are Associated with Altered Resting State Networks
Joey Contreras, Joaquín Goñi, Shannon Risacher, John West, Brenna McDonald, Martin Farlow, Olaf Sporns, Andy Saykin

IC-03-04 Network-Based Tau Deposition Patterns Are Related to Functional Network Failure Largely Via Beta-Amyloid Across the Alzheimer’s Spectrum
David Jones, Val Lowe, Heather Wiste, Matthew Senjem, Jonathan Graff Radford, Bradley Boeve, David Knopman, Ronald Petersen, Clifford Jack

IC-03-05 EEG Directed Connectivity from Posterior Brain Regions Is Decreased in Dementia with Lewy Bodies: A Comparison with Alzheimer’s Disease and Controls
Meenakshi Dauwan, Edwin Van Dellen, Lotte van Boxtel, Elisabeth van Straaten, Hanneke de Waal, Afina Lemstra, Alida Gouw, Wiesje van der Flier, Philip Scheltens, Iris Sommer, Cornelis Stam

4:30 – 5 p.m.

Presentation of the Neuroimaging Awards

5 – 5:30 p.m.

Closing Remarks
Liana Apostolova, University of California, Los Angeles, Los Angeles, Calif., United States; Indiana University School of Medicine, Indianapolis, Ind., United States


*Agenda subject to change.

Neuroimaging PIA Business Meeting

The ISTAART Neuroimaging PIA Business Meeting will take place immediately following AIC at 5:45 p.m. (the meeting room will be located in a nearby hotel).

Target audience

All clinicians involved in the care or research of individuals with memory or other cognitive complaints, including but not limited to neurologists, psychiatrists, radiologists, geriatricians, neuropsychologists, physicians and nurses; researchers, industry and regulatory agency stakeholders; and others involved in the use of imaging techniques in the study of Alzheimer’s disease, related disorders and normal aging.

Registration

AIC is a preconference to AAIC 2016. Preconferences require a separate registration fee in addition to AAIC full conference registration or it may be purchased as a stand-alone event. View registration information.

About ISTAART

ISTAART logoThe Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) is a professional society for individuals interested in Alzheimer's and dementia science—including scientists, physicians and other professionals involved in the causes and treatments of Alzheimer's disease and other dementias. ISTAART membership makes AAIC even better: receive discounted registration, participate in professional interest areas (PIA), attend PIA Day scientific sessions (Saturday, July 23) and attend exclusive member-only scientific and networking events. Members also receive ongoing benefits throughout the year, including an online monthly subscription to Alzheimer's & Dementia: The Journal of the Alzheimer's Association, free online access to Neurobiology of Aging, access to the online career center, monthly e-newsletters, networking forums and extended LOI deadlines for the Alzheimer's Association International Research Grant Program.

Non-members are encouraged to learn more and join ISTAART. Non-members may also join ISTAART during AAIC registration -- select "Member +PLUS" or "Student Member +PLUS " as the AAIC registration category to purchase one year of ISTAART membership in addition to AAIC registration at the member rate. Available to new members only.


Save on AAIC Registration with Group Rates

Bring your whole team to AAIC 2016. Discounted group rates are available for 10 or more colleagues or five or more students from the same lab group.



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