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Alzheimer's Imaging Consortium

Saturday, July 13, 2013
8:25 a.m.-5 p.m.
Presented by the ISTAART Neuroimaging Professional Interest Area
Boston Convention & Exhibition Center, 210ABC

 

 

Overview Continuing Medical Education
Target audience Accreditation statement
Learning objectives Credit designation
Schedule & Speakers Disclosure of conflicts of interest
Awards  

 

 

Gil Rabinovici, Chair, University of California, San Francisco, United States 
Christopher RoweChair, Austin Health, Melbourne, Australia

The Alzheimer's Imaging Consortium (AIC) pre-conference will focus on the clinical application and methodological development of neuroimaging (MRI, PET, SPECT, CT and others) to Alzheimer's disease, other dementias and normal brain aging. The meeting will consist of invited speakers, as well as oral and poster presentations from submitted abstracts. Presentations from young scientists and interactive discussion will be encouraged. The world's leading imaging and non-imaging researchers will discuss topics such as:

This event is organized by the ISTAART Neuroimaging Professional Interest Area.

Target audience

All researchers and clinicians involved in the care of or research on individuals with memory or other cognitive complaints, including but not limited to neurologists, psychiatrists, radiologists, geriatricians and neuropsychologists; as well as researchers, industry and regulatory agencies stakeholders; and others involved in the use of imaging techniques in the study of Alzheimer's disease, related disorders and normal aging.

Learning objectives

At the end of this educational activity, attendees should be able to:

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Schedule and Speakers

   


 

8:25 a.m.

Introductions

8:30-9:45 a.m.

IC-O1 Imaging Populations at Genetic Risk for Alzheimer's Disease

 

IC-O1-01 Presymptomatic Functional Brain Changes in PS1 E280A Mutation Carriers Compared to Other Biomarkers: Pilot Data From the Alzheimer's Prevention Initiative Biomarker Project

 

 

Adam Fleisher, Kewei Chen, Yakeel Quiroz, Laura Jakimovich, Madelyn Gutierrez, Jessica Langbaum, Auttawut Roontiva, Pradeep Thiyyagura, Ji Luo, Xiaofen Liu, Wendy Lee, Napatkamon Ayutyanont, Stephanie Parks, Claudia Munoz, Sonia Moreno, Natalia Acosta-Baena, Margarita Giraldo, Pierre Tariot, Francisco Lopera, Eric Reiman

 

IC-O1-02 Are Early Atrophy Patterns in Autosomal Dominant Familial Alzheimer's Disease Gene Dependent?

 

 

Kirsi Kinnunen, Natalie Ryan, David Cash, António Bastos Leite, Sarah Finnegan, Manuel Cardoso, Kelvin Leung, Marc Modat, Tammie Benzinger, Clifford Jack, Daniel Marcus, Marcus Raichle, Paul Thompson, John Ringman, Bernardino Ghetti, Stephen Salloway, Reisa Sperling, Peter Schofield, Colin Masters, Richard Mayeux, Ralph Martins, Michael Weiner, Randall Bateman, Alison Goate, Anne Fagan, Nigel Cairns, Virginia Buckles, John Morris, Martin Rossor, Sebastien Ourselin, Nick Fox

 

IC-O1-03 Hippocampal Transcriptome-Guided Gene-Gene Interaction of Memory Phenotype in MCI and Alzheimer’s Disease

 

 

Jingwen Yan, Sungeun Kim, Kwangsik Nho, Rui Chen, Shannon Risacher, Jason Moore, Andrew Saykin, Li Shen

 

IC-O1-04 Reduced Amyloid Deposition and Greater Hypometabolism in APOE-?4–Positive People with Alzheimer’s Disease

 

 

Manja Lehmann, Pia Ghosh, Cindee Madison, Anna Karydas, Giovanni Coppola, Bruce Miller, William Jagust, Gil Rabinovici

 

IC-O1-05 APOE-e4 is Associated With Increased Hippocampal Atrophy Rates in Alzheimer's Disease

 

 

Emily Manning, Josephine Barnes, David Cash, Jonathan Bartlett, Kelvin Leung, Sebastien Ourselin, Nick Fox

 

IC-O1-05 APOE-ε4 is Associated With Increased Hippocampal Atrophy Rates in Alzheimer's Disease

 

 

Emily Manning, Josephine Barnes, David Cash, Jonathan Bartlett, Kelvin Leung, Sebastien Ourselin, Nick Fox

9:45-10:15 a.m.

PL-01 Brain Imaging in Preclinical Study and Prevention of Alzheimer's Disease?

Eric M. Reiman, Banner Alzheimer's Institute, Phoenix, Ariz., United States

10:15–10:30 a.m.

Break

 

10:30–11 a.m.

PL-02 Developing a Translational Toolbox for Parkinson Disease: The Parkinson Progression Marker Initiative

Kenneth Marek, The Institute for Neurodegenerative Disorders, New Haven, Conn., United States

11a.m.-12:30 p.m.

IC-02 Normal Aging and Early Detection of Alzheimer's Disease

 

IC-O2-01 How Do We Define Amyloid Positivity in an Asymptomatic Population? Comparison of CSF, Quantitative PET and Clinical PET Examinations

 

 

Brian Rubin, Yi Su, Jonathan McConathy, Tyler Blazey, Rosana Ponisio, Jin Weng, Russ Hornbeck, Anne Fagan, Chengjie Xiong, John Morris, Tammie Benzinger

 

IC-O2-02 Detecting Cognitive Evidence of Preclinical Alzheimer's Disease

 

 

Dorene Rentz, Trey Hedden, Elizabeth Mormino, Rebecca Amariglio, John Becker, Aaron Schultz, Gad Marshall, Reisa Sperling, Keith Johnson

 

IC-O2-03 The Effects of Aging on Whole Brain Functional Connectivity

 

 

Matthew Brier, Jewell Thomas, Liang Wang, Tammie Benzinger, John Morris, Beau Ances

 

IC-O2-04 Association between Regional Task-Free Fmri Synchrony and AD Imaging Biomarkers in Cognitively Normal Subjects

 

 

Prashanthi Vemuri, David Thomas Jones, Jeffrey L Gunter, Scott A Przybelski, Brian E Gregg, Mary M Machulda, Mathew L Senjem, Val J. Lowe, David S Knopman, Ronald C Petersen, Clifford R Jack

 

IC-O2-05 Development of White Matter Lesions is Preceded by Changes in Normal-Appearing White Matter

 

 

Marius de Groot, Benjamin Verhaaren, Renske de Boer, Stefan Klein, Albert Hofman, Aad van der Lugt, Mohammad Ikram, Wiro Niessen, Meike Vernooij

 

IC-O2-06 Perfusion and Structural MRI Correlates of Brain Amyloidosis in Early MCI

 

 

Duygu Tosun, Michael Weiner

 

12:30-2:30 p.m.

Lunch and Poster Viewing/Poster Judging
12:30-1:30 p.m. - Odd poster numbers
1:30-2:30 p.m. - Even poster numbers

2:30-3:45 p.m.

IC-O3 Emerging Techniques

 

IC-O3-01 The Centiloid Scale: Standardization of Amyloid Imaging Measures

 

 

Christopher Rowe, William Klunk, Robert Koeppe, William Jagust, Michael Pontecorvo, Michael Devous, Marybeth Howlett, Daniel Skovronsky, Keith Johnson, Julie Price, Chet Mathis, Mark Mintun

 

IC-O3-02 Plaque-Binding Magnetic Nanoparticles for Early Diagnosis of Alzheimer's Disease by Magnetic Resonance Imaging (MRI)

 

 

Kwok Kin Cheng, Larry Baum

 

IC-O3-03 The Relationship Between Hippocampal Atrophy and Neuropathology Markers: A 7T MRI Study

 

 

Liana Apostolova, Sona Babakchanian, Somme Johanne, Hedieh Honarpisheh, Kristy Hwang, Kristina Biado, Spencer Tung, Andrew Frew, Jeffry Alger, Jonathan Wisco, Stephen Schettler, Chris Zarow, Harry Vinters, Paul Thompson

 

IC-O3-04 In-Vivo Characterization of Glutamatergic Vulnerability in Behavioral Variant FTD: An [11C]ABP688 PET/ VBM /DBM Study

 

 

Antoine Leuzy, Jared Rowley, Laksanun Cheewakriengkrai, Monica Shin, Seqian Wang, Maxime Parent, Eduardo Zimmer, Marina Dauar, Pedro Rosa-Neto, Serge Gauthier

 

IC-O3-05 Task-Free fMRI in Clinical Trials: Selection of Covariates and Numeric Endpoints

 

 

Adam Schwarz, Basile Pinsard, Vincent Perlbarg, Yuefeng Lu, Lea Marais, Derek Hill, Jean-Francois Mangin, Adam Schwarz

3:45-4:15 p.m.

Panel Discussion—The Role of Neuroimaging in AD Drug Development: Lessons from Recent Clinical Trials

Moderator
Nick Fox, Alzheimer’s Research UK, London, United Kingdom

Panelists
Paul Aisen, University of California, La Jolla, Calif., United States
Maria Carillo, Alzheimer’s Association, Chicago, Ill., United States
Howard Feldman, Yale School of Medicine, New Haven, Conn., United States
Eric Karran, Alzheimer’s Research UK, London, United Kingdom
Philip Scheltens, VU University Medical Center, Amsterdam, the Netherlands
Eric Siemers, Eli Lilly & Company, Indianapolis, Ind. United States
Reisa Sperling, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, Mass., United States

4:15-4:45 p.m.

Neuroimaging Prize Announcements/Presentations

4:45-5 p.m.

Best poster and oral announcement

 

   

 

Awards

(the application process is now closed)

A limited number of fellowships (in the form of complimentary AIC registration) are available for young researchers who submit an abstract. Awardees will be chosen based on the anonymous reviewers' ratings of their oral or poster abstract and financial need. Additionally, the best oral and poster presentation among this group will be awarded a $500 prize each.

Continuing Medical Education

This activity is jointly sponsored by the Postgraduate Institute for Medicine (PIM) and the Alzheimer's Association.
Description: PIM Postgraduate Institute for Medicine
Scientific sessions are not supported by any commercial entity.

Accreditation statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Postgraduate Institute for Medicine and the Alzheimer's Association. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit designation

The Postgraduate Institute for Medicine designates this live activity for a maximum of 5.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of conflicts of interest

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. The existence or absence of COI for everyone in a position to control content will be disclosed to participants prior to the start of each activity.


Apply for a fellowship

A limited number of travel fellowships are available to AAIC presenting authors.
Learn more >>
AIC fellowships >>


 

2013 Imaging Consortium Sponsors

General Electic Health Care
Navidea