Phase II, Multicenter, Sixteen-Week, Randomized, Double Blind, Placebo-Controlled Evaluation of the Efficacy, Tolerability and Safety of Memantine Hydrochloride on Enhancing the Cognitive Abilities of Adolescents and Young Adults with Down Syndrome- Study Subjects Wanted
A team of medical doctors and psychologists at the Case Western Reserve University, University Hospitals, and the Cleveland Clinic is investigating the effects of memantine on individuals with Down syndrome who are between the ages 15 and 32. Memantine is a medication FDA-approved for the treatment of Alzheimer's disease, but it is not approved for use in persons with Down syndrome. This study was designed to examine whether or not this medication is safe and if it can improve memory and learning skills in adolescents and young adults with Down syndrome.
This study requires the participant and his or her primary caregiver to complete five to seven outpatient visits to University Hospitals in Cleveland, Ohio. Psychological and medical tests will take place during the visits. The tests, medication, and medical care related to the study are provided free of charge. Parking will be validated, and mileage can be reimbursed for those traveling 20 miles or more to come to the study.
If you, or someone you know, would be interested and meet the following requirements:
The study Principal Investigator is Alberto Costa, MD, PhD
For more information, please call or E-mail the study coordinator, Ms. Melissa Stasko (216-844-7281, Melissa.Stasko@case.edu)
FAMILY CAREGIVERS FOR
Purpose: To learn about the activities pairs of family caregivers help with and their attitudes and feelings towards providing care/assistance.
Please call (216) 395-7247 or complete this form.
Questions or concerns contact:
Jessica Alva, M.A., Graduate Student
T.J. McCallum, Ph.D., Faculty Advisor
(216) 395-PAIR / (216) 395-7247
Alzheimer's Disease: NeuroAD Clinical Trial
Patients may qualify for this study if they:
The NeuroAD Study is testing a non-invasive therapeutic system designed to improve cognitive functioning through magnetic stimulation to targeted areas of the brain. In addition, cognitive training is done simultaneously using a interactive video screen. It is a 15 week program consisting of daily 1 hour appointments, five days a week for 6 weeks; two screening visits including an MRI; and two follow up visits, one at 7 weeks and the other at 12 weeks.
If you are interested in participating or would like additional information, please contact the study coordinator, Christine Whitman, RN.
216.227.2438 or firstname.lastname@example.org
Families Affected by Dementia
Do you have a relative who is 60 years or older with dementia or age-related memory impairment?
Are you a live-in, unpaid caregiver for this family member?
If so, you may be eligible to participate in a telephone survey. Upon completion of the survey, you will be compensated $40 for your time.
Call the Aging Family Project University of Miami
Have an Alzheimer’s disease diagnosis, mild cognitive impairment, or think you may have Alzheimer’s disease?
Current available medications help manage symptoms but do not slow the course of Alzheimer’s disease. Through ongoing clinical research, doctors evaluate study drugs that may control symptoms and, may possibly help with disease management.
We are evaluating the effectiveness and safety of an oral study drug that may help slow the progression of mild to moderate Alzheimer’s Disease.
To be considered for study participation, you must:
All study-related drugs and care will be provided at no cost.
Please contact Elisa @ (216) 832-6606.
Research Study seeks interested Individuals at least 70 years old with no memory problems or with mild to moderate memory problems are invited to take part in a research study.*
Drs. Kathleen Smyth and Martha Sajatovic of the Neurological Outcomes Center are the study’s Principal Investigators. The goal of this study is to find the best way to measure the effects of future treatments to improve physical and mental function of older adults.
The study is funded by the National Institutes of Health.
For more information please contact
*endorsed by Greater Michigan Chapter MSAC
Cyndi Hovland-Scafe, former Family Services Manager for the Greater Michigan Chapter and social work student at the University of Wisconsin-Madison, is exploring caregivers' experiences with the death of a family member from a dementia-related diagnosis. It is hoped that the results of this study will help professionals to understand better the physical, emotional, social and spiritual needs of family members caring for a loved one at the end of his or her life.
If so, would you be willing to share your experiences with Cyndi? To participate in this study, Cyndi would meet with you at your home or other convenient location for a 60-90 minute interview. For more information or to volunteer please contact:
Alzheimer’s Disease & Cataract Removal Research Study
University Hospitals Case Medical Center, the MetroHealth Medical System, and Case Western Reserve University are now enrolling patients in a new, 5-year research study sponsored by the National Institutes of Health.
In the study, we will learn more about how cataract removal impacts Alzheimer’s disease patients in their daily activities, their quality of life, their mood, and their performance on memory, cognitive, and visual tasks.
The duration of the study for each Participant will be approximately 6 months. All study Participants will first be screened to determine if they are eligible and then randomly selected into one of two groups: Group A (immediate surgery group), or Group B (delayed surgery group). Group A will have their cataract surgery within 1 month of enrolling in the study. Group B will be asked to delay their cataract surgery for 6 months.
To be eligible, you must be at least 50 years or older, have a diagnosis of Alzheimer’s disease, have cataracts in both eyes, and know someone who can act as your “study partner.”
To learn more about this study, please contact the University Hospitals Study Coordinator, Tatiana Riedel at 216-368-6465, (e-mail email@example.com), or the MetroHealth Study Coordinator, Alicia O’Brien at 216-778-2461 (e-mail firstname.lastname@example.org).
Participants needed for
Are you generally healthy, between the ages of 60 and 85, and have had a family member diagnosed with Alzheimer’s Disease? If so, you may be eligible for a new study being conducted at the Lou Ruvo Cleveland Clinic Center for Brain Health.
Please download the following 2 PDFs for more information about the study and how to participate