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Funded Studies: 2008


AUSTRALIA

Gilles J. Guillemin, Ph.D.
University of New South Wales
Sydney, Australia
Identification of a New Neurodegenerative Mechanism in Alzheimer's Disease
Investigator-Initiated Research Grant―$228,453 over three years

Andrew F. Hill, Ph.D.
University of Melbourne
Parkville, Australia
Investigating Exosomes as Novel Secretory Carriers of APP and Abeta
New Investigator Research Grant―$99,000 over two years

Christopher Rowe, Ph.D.
Austin Health
Heidelberg, Australia
Transfer of Data from AIBL to ADNI
Australian Imaging, Biomarkers and Lifestyle Study of Aging (AIBL)―$340,000 over two years

BELGIUM

Willem G. Annaert, Ph.D.
Flanders Interuniversity Institute for Biotechnology
Leuven, Belgium
Targeting and Localization of Distinct Gamma-Secretase Complexes Versus APP Investigator-Initiated Research Grant―$240,000 over three years

BRAZIL

Orestes Forlenza, Ph.D.
Universidade de São Paulo
São Paulo, Brazil
Disease-Modifying Properties of Lithium in Alzheimer's Disease
New Investigator Research Grant―$100,000 over two years

CANADA

Vladimir Hachinski, D.Sc.
University of Western Ontario
London, Ontario
Canada
Risk Score Development to Predict Alzheimer's Disease and Dementia
Investigator-Initiated Research Grant―$238,770 over three years

Alex Mihailidis, Ph.D.
University of Toronto
Toronto, Ontario
Canada
Toward a Pervasive Prompting System: Improving and Expanding the COACH
Everyday Technologies for Alzheimer Care―$196,324 over three years

Pascal Poupart, Ph.D.
University of Waterloo
Waterloo, Ontario
Canada
Composite Behavioral Markers to Assess and Monitor Alzheimer's Disease
Everyday Technologies for Alzheimer Care―$200,000 over three years

Pedro Rosa-Neto, Ph.D.
McGill University
Montreal, Quebec
Canada
Glutamatergic Abnormalities in Patients with Early Alzheimer's Disease
New Investigator Research Grant―$98,000 over two years

Rebecca J. Rylett, Ph.D.
University of Western Ontario
London, Ontario
Canada
Modulation of Neuronal Gene Expression by Choline Acetyltransferase
Investigator-Initiated Research Grant—$240,000 over three years

CHILE

Ricardo Maccioni, Ph.D.
International Center for Biomedicine
Santiago, Chile
In Search of Tau-Binding Molecules with Potential Clinical Applications
Investigator-Initiated Research Grant―$238,800 over three years

DENMARK

Olav Andersen, Ph.D.
University of Aarhus
Aarhus, Denmark
Influence on APP Processing by the Sorting Complex of SorLA and Retromer
New Investigator Research Grant―$100,000 over two years

HUNGARY

Andras L. Palotas, M.D., Ph.D.
Asklepios-Med Bt.
Szeged, Hungary
Early Diagnosis Using Fibroblasts and Lymphocytes in Alzheimer's Disease
New Investigator Research Grant—$97,912 over two years

ISRAEL

Moussa Ben Hur Youdim, Ph.D.
Technion–Israel Institute of Technology
Haifa, Israel
Novel Neuroprotective and Neurorestorative Drugs for Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

ITALY

Helene Marie, Ph.D.
European Brain Research Institute
Rome, Italy
Does NGF Deprivation Lead to Glutamatergic/GABAergic Network Imbalance?
New Investigator Research Grant—$98,450 over two years

Michele Zoli, M.D.
Università di Modena e Reggio Emilia
Modena, Italy
Genetic Deletion of Hippocampal Precursors in a Transgenic Model of AD
Investigator-Initiated Research Grant—$198,000 over three years

JAPAN

Yoshihiro Konishi, M.D., Ph.D.
National Hospital Organization Tottori Medical Center
Tottori, Japan
Comparison of Beta-Secretase Between Alzheimer Brain in the U.S. and Japan
New Investigator Research Grant—$96,000 over two years

SOUTH KOREA

Yong-Keun Jung, Ph.D.
Seoul National University
Seoul, South Korea
Novel Activator Genes of Gamma-Secretase for APP-Favorable Cleavage
Investigator-Initiated Research Grant—$240,000 over three years

SWEDEN

Henrik Zetterberg, M.D., Ph.D.
Sahlgrenska Academy at Göteborg University
Molndal, Sweden
Targeted Proteomics of Cerebrospinal Fluid Amyloid-Beta Fragments in Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

THE NETHERLANDS

Aad Van Der Lugt, Ph.D.
Erasmus Medical College
Rotterdam, Netherlands
Arterial Calcifications and Risk of Dementia
New Investigator Research Grant—$100,000 over two years

UNITED KINGDOM

Arlene Astell, Ph.D.
University of St. Andrews
St. Andrews, United Kingdom
Prompting to Support Independence in Dementia
Everyday Technologies for Alzheimer Care—$179,634 over two years

UNITED STATES

Alabama

Muralikrishnan Dhanasekaran, Ph.D.
Auburn University
Auburn, Alabama
Novel Neuroprotective Effects of Centella Asiatica
New Investigator Research Grant—$99,990 over two years

Mathieu Lesort, Ph.D.
University of Alabama at Birmingham
Birmingham, Alabama
Pathological Interactions in Diabetes and Alzheimer's Disease
Investigator-Initiated Research Grant—$200,000 over three years

Arizona

Lih-Fen Lue, Ph.D.
Sun Health Research Institute
Sun City, Arizona
Deficiency of Circulating Soluble Receptor RAGE in Subjects with Mild Cognitive Impairment
Investigator-Initiated Research Grant—$238,843 over three years

California

Mark Bondi, Ph.D.
University of California, San Diego
San Diego, California
Functional Neuroanatomy of Memory in Elders: A Combined FMRI and DTI Study
Investigator-Initiated Research Grant—$239,988 over three years

David H. Cribbs, Ph.D.
University of California, Irvine
Irvine, California
Reducing the Risk of Cerebral Vascular Adverse Events in Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

Dolores E. Gallagher-Thompson, Ph.D.
Stanford University
Stanford, California
Development and Evaluation of a Fotonovela to Manage Difficult Behaviors
Investigator-Initiated Research Grant—$240,000 over three years

William Jagust, M.D.
University of California, Berkeley
Berkeley, California
The Detection of Alzheimer's Disease in Normal Older People
Zenith Fellows Award—$449,999 over three years

Kwang Mook Jung, Ph.D.
University of California, Irvine
Irvine, California
Deficits in Anandamide Signaling Underlie Cognitive Dysfunction in Alzheimer's Disease
Investigator-Initiated Research Grant—$239,714 over three years

David E. Kang, Ph.D.
University of California, San Diego
La Jolla, California
Targeting the LRP Pathway for Abeta Reduction from Inside and Outside
Investigator-Initiated Research Grant—$240,000 over three years

Stanislav L. Karsten, Ph.D.
University of California, Los Angeles
Torrance, California
Neuroprotective Role of Puromycin-Sensitive Aminopeptidase
New Investigator Research Grant—$100,000 over two years

Michael D. Lee, Ph.D.
University of California, Irvine
Irvine, California
Bayesian Methods for the Detection, Diagnosis and Treatment of Alzheimer's
New Investigator Research Grant—$87,726 over two years

Pamela A. Maher, Ph.D.
Salk Institute for Biological Studies
La Jolla, California
Fisetin and Derivatives as Neuroprotective Drugs for Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

William Mobley, M.D., Ph.D.
The Regents of the University of California, San Diego
San Diego, California
Degeneration of Hippocampal Circuits in Down Syndrome: a Role for APP?
Investigator-Initiated Research Grant—$239,901 over three years

Susanna Rosi, Ph.D.
University of California, San Francisco
San Francisco, California
Altered Neuronal-Microglia Communication Impacts Neuronal Function
New Investigator Research Grant—$100,000 over two years

Subhojit Roy, Ph.D.
University of California, San Diego
San Diego, California
Mechanisms of Axonal Transport Dysfunction in Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

Mark H. Tuszynski, Ph.D.
University of California, San Diego
La Jolla, California
Therapeutic Effects of BDNF in APP Mutant Mice
Investigator-Initiated Research Grant—$240,000 over three years

Kristine Yaffe, M.D.
University of California, San Francisco
San Francisco, California
Predictors of Mild Cognitive Impairment/Dementia Among the Oldest Old Women
Investigator-Initiated Research Grant—$240,000 over three years

Jerry C. Yang, Ph.D.
University of California, San Diego
La Jolla, California
Exploring Methods to Chemically Degrade Aggregated Abeta Peptides
New Investigator Research Grant—$100,000 over two years

Colorado

Nicholas W. Seeds, Ph.D.
University of Colorado, Denver, Anschutz Medical Campus
Aurora, Colorado
Plasminogen Activator and Its Inhibitors in Alzheimer's Disease
Investigator-Initiated Research Grant—$200,000 over two years

Connecticut

John Seibyl, M.D.
Institute for Neurodegenerative Disorders
New Haven, Connecticut
Imaging Noradrenergic Function in Alzheimer's Disease
Investigator-Initiated Research Grant—$236,544 over three years

Florida

Valentina Echeverria Moran, Ph.D.
Bay Pines Foundation, Inc.
Bay Pines, Florida
Molecular Mechanisms Underlying the Neuroprotective Actions of Cotinine
New Investigator Research Grant—$100,000 over two years

Bonnie Goodwin, Ph.D.
University of South Florida
Tampa, Florida
Gamma-Secretase Inhibitors Induce Cell Cycle Defects and Chromosome Aneuploidy
New Investigator Research Grant—$100,000 over two years

Seong-Hun Kim, Ph.D.
University of Florida
Gainesville, Florida
Role of Rer1 in the Regulation of Gamma-Secretase Trafficking and Activity
Investigator-Initiated Research Grant—$240,000 over three years

Yona Levites, Ph.D.
University of Florida
Gainesville, Florida
Single Chain Fragments as a Tool to Target Generic Amyloid
New Investigator Research Grant—$100,000 over two years

Jaya Padmanabhan, Ph.D.
University of South Florida
Florida
Regulatory Functions of Inflammatory Proteins in Alzheimer's Disease
Investigator-Initiated Research Grant―$240,000 over three years

Daniel Paris, Ph.D.
Roskamp Institute
Sarasota, Florida
Effect of Celastrol in a Transgenic Mouse Model of Alzheimer's Disease
Investigator-Initiated Research Grant—$200,000 over two years

Hawaii

Philip Williams, Ph.D.
University of Hawaii
Honolulu, Hawaii
Medicines from Marine Sources
New Investigator Research Grant—$99,977 over two years

Illinois

Douglas L. Feinstein, Ph.D.
University of Illinois, Chicago
Chicago, Illinois
Anti-Amyloidogenic Effects of Noradrenaline
Investigator-Initiated Research Grant—$239,999 over three years

Adriana Ferreira, M.D., Ph.D.
Northwestern University, Chicago
Chicago, Illinois
Cholesterol and the Susceptibility of Aging Neurons to ABeta Toxicity
Investigator-Initiated Research Grant—$240,000 over three years

Yoshitaka Ishii, Ph.D.
University of Illinois at Chicago
Chicago, Illinois
Toxicity and Structure of Aggregated Alzheimer's Beta-Amyloid
Investigator-Initiated Research Grant—$240,000 over three years

Sergey Kalinin, M.D.
University of Illinois at Chicago
Chicago, Illinois
Locus Coeruleus Damage During Normal Aging and in Transgenic Models of Alzheimer's Disease
New Investigator Research Grant—$99,999 over two years

Mary Jo LaDu, Ph.D.
University of Illinois, Chicago
Chicago, Illinois
The Effect of ApoE Isoform on Intraneuronal ApoE/Abeta42 Interactions
Zenith Fellows Award—$450,000 over three years

Robert A. Marr, Ph.D.
Rosalind Franklin University of Medicine and Science
North Chicago, Illinois
Investigation of the Role of MMEL in Protection from Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

Susan O. McGuire, Ph.D.
The Board of Trustees of the University of Illinois - Chicago
Chicago, Illinois
Loss of C5L2 and NFT Formation: Conversion of Mild Cognitive Impairment to Alzheimer's Disease
Investigator-Initiated Research Grant—$239,323 over three years

Ken A. Paller, Ph.D.
Northwestern University, Evanston
Evanston, Illinois
Memory Processing During Sleep in Alzheimer's Disease
The Senator Mark Hatfield Award for Clinical Research in Alzheimer's Disease—$240,000 over three years

Peter Penzes, Ph.D.
Northwestern University, Chicago
Chicago, Illinois
Modeling Synapse Dysgenesis–Linked Memory Impairment in Alzheimer's Disease
Investigator-Initiated Research Grant—$239,764 over three years

Grace Stutzmann, Ph.D.
Rosalind Franklin University of Medicine and Science
North Chicago, Illinois
Neuronal Ca2+ Dysregulation as a Pathogenic Factor in Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

Gopal Thinakaran, Ph.D.
University of Chicago
Chicago, Illinois
Altering Microdomain Localization of Gamma-Secretase in Transgenic Mice
Investigator-Initiated Research Grant—$240,000 over three years

Kulandaivelu S. Vetrivel, Ph.D.
University of Chicago
Chicago, Illinois
Exploring Beta-Secretase Actvity in Lipid Raft Microdomains
New Investigator Research Grant—$100,000 over two years

Kansas

Shi Du Yan, M.D.
The University of Kansas Center for Research, Inc.
Kansas
Cyclophilin D as a Mitochondrial Target of Alzheimer's Disease
Investigator-Initiated Research Grant―$240,000 over three years

Kentucky

Louis B. Hersh, Ph.D.
University of Kentuck Research Foundation
Lexington, Kentucky
A Modified Neprilysin for Gene Therapy
Investigator-Initiated Research Grant—$238,936 over three years

Peter T. Nelson, M.D., Ph.D.
University of Kentucky Research Foundation
Lexington, Kentucky
Mechanism and Therapeutic Significance of an Alzheimer's Disease–Relevant MicroRNA Pathway
New Investigator Research Grant—$100,000 over two years

Louisiana

Donald K. Ingram, Ph.D.
Louisiana State University Agricultural and Mechanical College/Pennington Biomedical Research Center
Baton Rouge, Louisiana
Developing Calorie Restriction Mimetics for Treating Alzheimer's Disease
Investigator-Initiated Research Grant—$239,426 over three years

Maryland

Kathryn de Medeiros, Ph.D.
Copper Ridge Institute
Sykesville, Maryland
The Social Environments of People with Dementia in Long-Term Care
New Investigator Research Grant—$99,389 over two years

Hochang Lee, M.D.
Johns Hopkins University School of Medicine
Baltimore, Maryland
Assessment of Burden of Dementia Among Korean Elders in Maryland
Investigator-Initiated Research Grant—$240,000 over three years

Quincy M. Samus, Ph.D.
Johns Hopkins University School of Medicine
Baltimore, Maryland
Specialization of Dementia Care Assisted Living: A Pilot Project
New Investigator Research Grant—$100,000 over two years

Massachusetts

Natalia A. Crivello, Ph.D.
Tufts University
Boston, Massachusetts
Folate Deficiency, Brain Lipids and Amyloid Toxicity in APP/PS1 Mice
New Investigator Research Grant—$98,997 over two years

Nancy B. Emerson-Lombardo, Ph.D.
Boston University
Bedford, Massachusetts
Nutritional Supplement Clinical Trial for Early Alzheimer's
Investigator-Initiated Research Grant—$240,000 over three years

Gilbert T. Feke, Ph.D.
Retina Associates Inc.
Boston, Massachusetts
Objective Biomarkers for Alzheimer's Disease in the Retina
Investigator-Initiated Research Grant—$239,390 over three years

Judith G. Gonyea, Ph.D.
Boston University
Boston, Massachusetts
Circulo de Cuidado: A Behavioral Group Intervention for Latino Families
Investigator-Initiated Research Grant—$239,080 over three years

Sharon K. Inouye, M.D.
Hebrew Rehabilitation Center for the Aged
Boston, Massachusetts
Impact of Hospitalization in Alzheimer's Disease: Risk Factors and Outcomes
Investigator-Initiated Research Grant—$240,000 over three years

Dorene M. Rentz, Psy.D.
Brigham and Women's Hospital, Inc.
Boston, Massachusetts
Amyloid Deposition in Normal Controls: Impact of Cognitive Reserve
Investigator-Initiated Research Grant—$239,569 over three years

Thomas B. Shea, Ph.D.
University of Massachusetts
Lowell, Massachusetts
A Phase II Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease
Investigator-Initiated Research Grant—$237,449 over three years

Volney Sheen, M.D., Ph.D.
Beth Israel Deaconess Medical Center
Boston, Massachusetts
In Vitro Modeling of Neuronal-Glial Interactions in Alzheimer's Disease
New Investigator Research Grant—$99,990 over two years

Robert A. Stern, Ph.D.
Boston University
Boston, Massachusetts
Assessment of Driving Safety in Aging, Mild Cognitive Impairment and Dementia
Investigator-Initiated Research Grant—$239,999 over three years

Angelo Volandes, M.D.
Massachusetts General Hospital
Boston, Massachusetts
Using Video Images of Dementia in Advance Care Planning
New Investigator Research Grant—$96,844 over two years

Michael S. Wolfe, Ph.D.
Brigham and Women's Hospital, Inc.
Boston, Massachusetts
Regulation of RNA Splicing in Alzheimer's and Related Dementias
Zenith Fellows Award—$450,000 over three years

Michigan

Jason E. Gestwicki, Ph.D.
University of Michigan
Ann Arbor, Michigan
Chemical Probes for Selective Recognition of Amyloid Oligomers
New Investigator Research Grant—$99,813 over two years

Missouri

Guojun Bu, Ph.D.
Mayo Clinic Jacksonville
St. Louis, Missouri
LRP1 and ApoE Isoforms in Brain Lipid Metabolism and Synaptic Functions
Zenith Fellows Award—$450,000 over three years

Chengjie Xiong, Ph.D.
Washington University in St. Louis
St. Louis, Missouri
The Earliest Antecedent Markers of Alzheimer's Disease
New Investigator Research Grant—$99,956 over two years

Nebraska

Prasad R. Padala, M.D.
University of Nebraska
Omaha, Nebraska
Improving Function, Quality of Life and Glycemia in Diabetics with Dementia
New Investigator Research Grant—$98,690 over two years

New Jersey

Michael Hecht, Ph.D.
Princeton University
Princeton, New Jersey
Discovery of Compounds that Prevent A-Beta Toxicity
Investigator-Initiated Research Grant—$239,993 over three years

New York

Fortunato Battaglia, Ph.D.
City College of New York and Research Foundation of the City University of New York
New York, New York
Boosting Memory in APP/PS1 Mice with Transcranial Magnetic Stimulation
New Investigator Research Grant—$99,000 over two years

Gilbert Di Paolo, Ph.D.
Columbia University Medical Center
New York, New York
Genetic Modulation of PIP2 in Alzheimer's Disease Mouse Models: Effect on Cognitive Decline
New Investigator Research Grant—$100,000 over two years

Wen-Biao Gan, Ph.D.
New York University School of Medicine
New York, New York
The Role of Microglia in Amyloid Plaque Clearance and Synaptic Pathology
Investigator-Initiated Research Grant—$240,000 over three years

Bing Gong, M.D.
Columbia University Medical Center
New York, New York
Fbx2-Mediated Ubiquitin Pathway: A Novel Route for BACE1 Degradation
Investigator-Initiated Research Grant—$240,000 over three years

Lawrence S. Honig, M.D., Ph.D.
Columbia University Medical Center
New York, New York
Changes in Telomere Length and the Risk of Alzheimer Disease
Investigator-Initiated Research Grant—$240,000 over three years

Yueming Li, Ph.D.
Sloan-Kettering Institute for Cancer Research
New York, New York
Modulation of the Gamma-Secretase Complex and Activity by Individual Subunits
Investigator-Initiated Research Grant—$240,000 over three years

David M. Lin, Ph.D.
Cornell University
Ithaca, New York
A Novel Mouse Model of Neurodegeneration
Investigator-Initiated Research Grant—$240,000 over three years

Fei Liu, Ph.D.
Research Foundation for Mental Hygiene, Inc. at New York State Institute for Basic Research
Staten Island, New York
Involvement of Dyrk1A in ASF-Regulated Alternative Splicing of Tau Exon 10
New Investigator Research Grant—$100,000 over two years

Bradley L. Nilsson, Ph.D.
University of Rochester
Rochester, New York
Probing Amyloid-Beta Structure and Aggregation with Non-Natural Amino Acids
New Investigator Research Grant—$99,998 over two years

Ipe Ninan, Ph.D.
New York University School of Medicine
New York, New York
Modulation of Synaptic Neurotransmission by Physiological Amyloid-Beta
New Investigator Research Grant—$99,956 over two years

James M. Noble, M.D.
Columbia University Medical Center
New York, New York
Arteriosclerosis and Alzheimer's in a Multiethnic Group of Autopsy Brains
New Investigator Research Grant—$95,501 over two years

Masuo Ohno, Ph.D.
Nathan S. Kline Institute for Psychiatric Research
Orangeburg, New York
Testing of Rab5-Overexpressing Mice as a Novel Alzheimer's Disease Model
Investigator-Initiated Research Grant—$240,000 over three years

Joann Reinhardt, Ph.D.
Jewish Home and Hospital for the Aged
New York, New York
Enhancing Life Quality for Residents with End-Stage Dementia and Families
Investigator-Initiated Research Grant—$237,067 over three years

Bernardo Rudy, M.D., Ph.D.
New York University School of Medicine
New York, New York
Neocortical Cholinergic Function in Alzheimer Mouse Models
Investigator-Initiated Research Grant—$198,000 over two years

Henry Rusinek, Ph.D.
New York University School of Medicine
New York, New York
Hippocampal Blood Flow and Vascular Reactivity in Normal Aging and Alzheimer's Disease
Investigator-Initiated Research Grant—$239,941 over three years

Martin J. Sadowski, M.D., Ph.D.
New York University School of Medicine
New York, New York
Therapeutic Monoclonal Antibodies for Prion Exposure Prophylaxis
Investigator-Initiated Research Grant—$240,000 over three years

Nicole Schupf, Ph.D.
Columbia University Medical Center
New York, New York
Genetics of Estrogen and Alzheimer's Disease in a Multiethnic Cohort
Investigator-Initiated Research Grant—$239,999 over three years

Qingli Shi, Ph.D.
Winifred Masterson Burke Medical Research Institute
White Plains, New York
Oxidative Stress/Gene Regulation of Mitochondrial Enzymes Implicated in Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

Einar M. Sigurdsson, Ph.D.
New York University School of Medicine
New York, New York
Tau Pathology: Therapy and In Vivo Imaging
Zenith Fellows Award—$450,000 over three years

Davide Tampellini, Ph.D.
Joan & Sanford I. Weill Medical College of Cornell University
New York, New York
Study of the Relation Between Synaptic Activity and Amyloid-Beta
New Investigator Research Grant—$99,660 over two years

Peter M. Tessier, Ph.D.
Rensselaer Polytechnic Institute
Troy, New York
Molecular Mechanisms of Abeta Aggregation Inhibitors
New Investigator Research Grant—$100,000 over two years

Youssef Z. Wadghiri, Ph.D.
New York University School of Medicine
New York, New York
Susceptibility-Based Magnetic Resonance Imaging Detection of Alzheimer's Amyloid
Investigator-Initiated Research Grant—$240,000 over three years

Dun-Sheng Yang, Ph.D.
Nathan S. Kline Institute for Psychiatric Research
Orangeburg, New York
Rescue Autophagic-Lysosomal Protein Degradation to Reverse Amyloid Pathology
Investigator-Initiated Research Grant—$239,968 over three years

North Carolina

Ashok N. Hegde, Ph.D.
Wake Forest University Health Sciences
Winston-Salem, North Carolina
Ameliorating Harmful Abeta Effects on Synaptic Plasticity and Memory
Investigator-Initiated Research Grant—$240,000 over three years

Terri Monk, M.D.
Duke University Medical Center
Durham, North Carolina
Does Inhalational Anesthesia Accelerate Postoperative Cognitive Decline?
Investigator-Initiated Research Grant—$240,000 over three years

Brenda L. Plassman, Ph.D.
Duke University Medical Center
Durham, North Carolina
Middle- and Late-Life Predictors of Alzheimer's Disease in Elderly Twins
Investigator-Initiated Research Grant—$198,363 over two years

Ilene C. Siegler, Ph.D.
Duke University Medical Center
Durham, North Carolina
Culture and the Emotional Health of Black and White Alzheimer Caregivers
Investigator-Initiated Research Grant—$238,729 over three years

Ryohei Yasuda, Ph.D.
Duke University Medical Center
Durham, North Carolina
Amyloid-Beta–Induced Rho GTPase Signaling in Dendritic Spines
New Investigator Research Grant—$100,000 over two years

Ohio

Jeffery B. Allen, Ph.D.
Wright State University
Dayton, Ohio
Impact of Quality of Education on the Cognitive Status of African-American Elders
Investigator-Initiated Research Grant—$185,526 over three years

David M. Bass, Ph.D.
Benjamin Rose Institute
Cleveland, Ohio
Partners in Dementia Care
Investigator-Initiated Research Grant—$239,811 over three years

Michelle Bourgeois, Ph.D.
Ohio State University
Columbus, Ohio
Determining Quality of Life in Dementia with Visual and Written Stimuli
Investigator-Initiated Research Grant—$200,000 over two years

Bruce T. Lamb, Ph.D.
Cleveland Clinic Foundation
Cleveland, Ohio
A Humanized Mouse Model of Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

McKee J. McClendon, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Quality of Caregiving in Alzheimer's Disease
Investigator-Initiated Research Grant—$239,996 over three years

Sanjay W. Pimplikar, Ph.D.
Cleveland Clinic Foundation
Cleveland, Ohio
The Role of APP Intracellular Domain in Neuronal Excitotoxicity
Investigator-Initiated Research Grant—$240,000 over three years

Sungok Yoon, Ph.D.
Ohio State University Research Foundation
Columbus, Ohio
Role of JNK3 in APP Trafficking
Investigator-Initiated Research Grant—$214,800 over three years

Oklahoma

Calin Prodan, M.D.
University of Oklahoma
Oklahoma City, Oklahoma
Coated Platelets: A Potential Biomarker for Alzheimer's Disease
New Investigator Research Grant—$99,968 over two years

Oregon

Holly B. Jimison, Ph.D.
Oregon Health & Science University
Portland, Oregon
Cognitive Health Coaching For Elders in a Home Environment
Everyday Technologies for Alzheimer Care—$189,842 over three years

Pennsylvania

Anand Hindupur, Ph.D.
University of Pennsylvania
Philadelphia, Pennsylvania
Mechanisms Underlying the Biogenesis of Mitochondrial Abeta
Investigator-Initiated Research Grant—$240,000 over three years

Koichi Iijima, Ph.D.
Thomas Jefferson University
Philadelphia, Pennsylvania
Mechanisms of Tau Phosphorylation and Toxicity Induced by Abeta42 In Vivo
New Investigator Research Grant—$99,999 over two years

Ronald Wetzel, Ph.D.
University of Pittsburgh
Pittsburgh, Pennsylvania
The Role of Amyloid-Beta Aggregate Polymorphism in Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

Rhode Island

Susan C. Miller, Ph.D.
Brown University
Providence, Rhode Island
End-of-Life Care and Hospice: Older Adults with Dementia in Nursing Homes
Investigator-Initiated Research Grant—$198,963 over two years

Tennessee

Angela L. Jefferson, Ph.D.
Vanderbilt University Medical Center
Nashville, Tennessee
Left Ventricular Function and Mild Cognitive Impairment
Investigator-Initiated Research Grant—$240,000 over three years

Texas

Jason Eriksen, Ph.D.
University of Houston
Houston, Texas
Role of PGRN in Microglial Activity in Alzheimer's Disease
New Investigator Research Grant—$99,970 over two years

Veronica Galvan, Ph.D.
University of Texas Health Sciences Center
San Antonio, Texas
Small-Molecule Inhibitors of Asp664 Cleavage of APP
New Investigator Research Grant—$148,660 over one year

Adriana M. Strutt, Ph.D.
Baylor College of Medicine
Houston, Texas
Validation of a Spanish Neuropsychological Dementia Battery
New Investigator Research Grant—$99,715 over two years

Giulio Taglialatela, Ph.D.
University of Texas Medical Branch at Galveston
Galveston, Texas
Neurobehavioral Toxicity of Natural Amyloid-Beta Oligomers
Investigator-Initiated Research Grant—$240,000 over three years

Washington

Matt Kaeberlein, Ph.D.
University of Washington
Seattle, Washington
TOR Signaling in Amyloid-Beta Toxicity
Investigator-Initiated Research Grant—$100,000 over two years

Wisconsin

Nashaat Gerges, Ph.D.
Medical College of Wisconsin
Milwaukee, Wisconsin
Role of Neurogranin in Alzheimer's Disease
New Investigator Research Grant—$100,000 over two years

Dengshun Wang, M.D., Ph.D.
University of Wisconsin-Madison
Madison, Wisconsin
Identifying Pathophysiologically Relevant Amyloid-Beta–Degrading Enzyme in Alzheimer's Disease
Investigator-Initiated Research Grant—$240,000 over three years

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