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Funded Studies: 2009


AUSTRALIA

Lindy M. Clemson, Ph.D.
The University of Sydney
Sydney, Australia
Using Personal and Environmental Resources to Reduce Falls Risk
New Investigator Research Grant – $80,000 over two years

BELGIUM

Jessie Theuns, Ph.D.
Flanders Interuniversity Institute for Biotechnology (VIB)
Antwerpen, Belgium
Molecular Genetics of Lewy Body Dementias
New Investigator Research Grant – $80,000 over two years

CANADA

Abedelnasser Abulrob, Ph.D.
University of Ottawa
Ottawa, Canada
Development of Agents and Imaging Modalities for Early Detection of AD
Molecular Imaging in Alzheimer's Disease – $380,780 over two years

CHINA

Jianzhi Wang, M.D.
Huazhong University of Science and Technology
Wuhan, China
Identification of a New Mechanism for Alzheimer-like Neurodegeneration
Investigator-Initiated Research Grant – $200,000 over three years

GREECE

Spiros Efthimiopoulos, Ph.D.
University of Athens
Ilisia, Greece
The Interrelationship of Ca2+ Homeostasis and APP/Homer Interaction
Investigator-Initiated Research Grant – $200,000 over three years

ITALY

Daniela Puzzo, M.D., Ph.D.
University of Catania
Catania, Italy
Amyloid-Beta is Necessary for Hippocampal Synaptic Plasticity and Memory
Investigator-Initiated Research Grant – $200,000 over three years

JAPAN

Hiroshi Mori, Ph.D.
Osaka City University Medical School
Osaka, Japan
Therapeutic Medication Using the Oligomer Abeta With the New AbetaE22delta
Investigator-Initiated Research Grant – $200,000 over three years

NETHERLANDS

Meike W. Vernooij, M.D.
Erasmus Medical Center
Rotterdam, Netherlands
Microstructural White Matter Changes and Risk of Cognitive Decline
New Investigator Research Grant – $80,000 over two years

SWEDEN

Louise Nygård, Ph.D.
Karolinska Institutet
Stockholm, Sweden
Design and Support Based on Knowing the Challenge of Skills and Technology
Everyday Technologies for Alzheimer Care – $160,000 over three years

Ingmar Skoog, M.D., Ph.D.
University of Gothenburg
Mölndal, Sweden
Dementia Among 85-Year-Olds Examined in 1986-87 and 2009
Investigator-Initiated Research Grant – $200,000 over three years

UNITED KINGDOM

Brian M. Austen, Ph.D.
St George's Hospital Medical School
London, United Kingdom
Brain Penetration of an MRI Contrast Reagent that Binds Beta-Amyloid
Molecular Imaging in Alzheimer's Disease – $399,767 over three years

UNITED STATES

Alabama

Inga Kadish, Ph.D.
The University of Alabama at Birmingham
Birmingham, Alabama
Long-Term Hypertension Contributes to the Development of Alzheimer Disease
New Investigator Research Grant – $80,000 over two years

Arkansas

Kalpana Padala, M.D.
Central Arkansas Veterans Healthcare System
Little Rock, Arkansas
Wii Fit for Improving Activity, Gait and Balance In Alzheimer's Dementia
New Investigator Research Grant – $80,000 over two years

California

Lea Grinberg, M.D., Ph.D.
University of California, San Francisco
San Francisco, California
Multi-Ethnic Neuropathological Comparison of AD: Focus on Control Cases
New Investigator Research Grant – $80,000 over two years

Zhefeng Guo, Ph.D.
University of California, Los Angeles
Los Angeles, California
EPR Studies of the Early Events in Abeta Aggregation
New Investigator Research Grant – $80,000 over two years

John Houde, Ph.D.
University of California San Diego – Bioengineering
San Diego, California
System for Assessing Speech Feedback Processing in Alzheimer's Disease
Everyday Technologies for Alzheimer Care – $160,000 over two years

Stefan Leutgeb, Ph.D.
University of California, San Diego
La Jolla, California
Neuronal Activity in the Entorhino-Hippocampal Circuitry in Early Stages
New Investigator Research Grant – $80,000 over two years

Debra Lieberman, Ph.D.
University of California, Santa Barbara
Santa Barbara, California
Lifestyle Improvement Game to Delay Alzheimer's Onset and Support Treatment
Everyday Technologies for Alzheimer Care – $160,000 over three years

Amy B. Manning-Bog, Ph.D.
Stanford Research Institute International
Menlo Park, California
The Role of DJ-1 in Cognitive Impairment
New Investigator Research Grant – $80,000 over two years

Sameer B. Shah, Ph.D.
University of California, San Diego-Neurobiology
La Jolla, California
Mechanical Determinants of Axonal Transport and Amyloid Processing
New Investigator Research Grant – $80,000 over two years

Christina Wierenga, Ph.D.
Veterans Medical Research Foundation
San Diego, California
Impact of APOE on Cerebral Perfusion and BOLD Response to Word Retrieval
New Investigator Research Grant – $80,000 over two years

Connecticut

Stephen M. Strittmatter, M.D., Ph.D.
Yale University
New Haven, Connecticut
Neuronal Receptor Mediating the Disease-Causing Effects of A-Beta Oligomers
Investigator-Initiated Research Grant – $200,000 over three years

Florida

Ren-Hua Chung, Ph.D.
University of Miami
Miami, Florida
A Novel Statistical Method Using Case-Control and Family Data
New Investigator Research Grant – $80,000 over two years

Yong Shen, M.D., Ph.D.
The Roskamp Institute Inc
Florida
Abnormal APP Processing in Living Cortical Neurons from AD Brains
Investigator-Initiated Research Grant – $200,000 over three years

Cynthia M. Stonnington, M.D.
Mayo Clinic Arizona
Scottsdale, Arizona
Does Zumba Improve Cognition in Healthy APOE e4 Carriers and Noncarriers?
New Investigator Research Grant – $80,000 over two years

Chad A. Dickey, Ph.D.
University of South Florida
Tampa, Florida
Chemical Inhibition of Hsp70 as a Therapeutic Strategy for AD
Investigator-Initiated Research Grant – $200,000 over three years

Karunya Kandimalla, Ph.D.
Florida Agricultural and Mechanical University
Tallahassee, Florida
Multifunctional Nanoprobe to Diagnose and Treat Cerebral Amyloid Angiopathy
New Investigator Research Grant – $80,000 over two years

Cheryl A. Luis, Ph.D.
The Roskamp Institute
Sarasota, Florida
Development of a Novel Screening Approach for MCI/Early AD
New Investigator Research Grant – $80,000 over two years

Margaret A. Pericak-Vance, Ph.D.
University of Miami School of Medicine
Miami, Florida
Identification of Rare Variants in Alzheimer Disease
Investigator-Initiated Research Grant – $200,000 over three years

Illinois

Paul E. Gold, Ph.D.
University of Illinois at Urbana-Champaign
Champaign, Illinois
Glucose, K-ATP Channels and Memory in Mouse Models of AD and DS
Investigator-Initiated Research Grant – $200,000 over three years

Dean M. Hartley, Ph.D.
Rush University Medical Center
Chicago, Illinois
Hyperexcited Neuro-Networks Drive the Progression of AD
Investigator-Initiated Research Grant – $200,000 over three years

William L. Klein, Ph.D.
Northwestern University, Evanston Campus
Evanston, Illinois
Therapeutic Protection Against Synapse-Targeting Abeta Oligomers
Zenith Fellows Award – $450,000 over three years

Yang Xiang, Ph.D.
University of Illinois at Urbana-Champaign
Urbana, Illinois
Amyloid Aβ Increases AMPAR-Mediated Synaptic Activity via b2AR Activation
New Investigator Research Grant – $80,000 over two years

Kentucky

Linda J. Van Eldik, Ph.D.
University of Kentucky Research Foundation
Lexington, Kentucky
Proinflammatory Cytokine Overproduction: A Contributor to Pathophysiology
Zenith Fellows Award – $450,000 over two years

Louisiana

Walter J. Lukiw, Ph.D.
Louisiana State University Health Sciences Center
New Orleans, Louisiana
Micro RNA-Mediated Neurotrophic & Synaptic Networks in Alzheimer's Disease
Investigator-Initiated Research Grant – $200,000 over three years

Maryland

Marilyn S. Albert, Ph.D.
Johns Hopkins University
Baltimore, Maryland
Placebo Data Analysis in AD and MCI Clinical Trials - Phase II
The Senator Mark Hatfield Award for Clinical Research in Alzheimer's Disease – $200,000 over three years

Elizabeth Galik, Ph.D.
University of Maryland
Baltimore, Maryland
Testing a Function Focused Nursing Intervention for Residents with Dementia
New Investigator Research Grant – $80,000 over two years

Juan C. Troncoso, M.D.
Johns Hopkins University
Baltimore, Maryland
Molecular Mechanisms Underlying Neuronal Hypertrophy in Asymptomatic AD
Investigator-Initiated Research Grant – $200,000 over three years

Massachusetts

Brian J. Bacskai, Ph.D.
Massachusetts General Hospital
Charlestown, Massachusetts
In Vivo Imaging of BBB Integrity to Enable CNS Probe Delivery
Molecular Imaging in Alzheimer's Disease – $388,362 over two years

Bradford Dickerson, M.D.
Massachusetts General Hospital
Charlestown, Massachusetts
Quantitative Neuroanatomic Biomarkers for Dementia Differential Diagnosis
Investigator-Initiated Research Grant – $200,000 over three years

Angela Ho, Ph.D.
Boston University
Boston, Massachusetts
Physiological Function of APP Proteins in the Adult Mammalian Brain
Investigator-Initiated Research Grant – $200,000 over three years

Bradley T. Hyman, M.D., Ph.D.
Massachusetts General Hospital
Charlestown, Massachusetts
Untangling Tangles in AD
Zenith Fellows Award – $449,778 over three years

Anna Krichevsky, Ph.D.
Brigham and Women's Hospital, Inc.
Boston, Massachusetts
MicroRNA Regulation of Early Events in Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Olivia Okereke, M.D.
Brigham and Women's Hospital, Inc.
Boston, Massachusetts
Planning Large-Scale Alzheimer Disease QUEstionnaire-Aided Studies-PLAQUES
New Investigator Research Grant – $80,000 over two years

Leon Reijmers, Ph.D.
Tufts University
Boston, Massachusetts
Imaging of Memory Circuits in the Presence of Soluble Amyloid-Beta
New Investigator Research Grant – $80,000 over two years

Jack T. Rogers, Ph.D.
Massachusetts General Hospital
Charlestown, Massachusetts
Post-Transcriptional Control of Alzheimer's APP and Brain Iron Homeostasis
Zenith Fellows Award – $447,300 over three years

Michigan

Catherine Collins, Ph.D.
University of Michigan
Ann Arbor, Michigan
The Role of JNK Signaling in APP Transport and Function
New Investigator Research Grant – $80,000 over two years

Minnesota

Ling Li, Ph.D.
Regents of the University of Minnesota
Twin Cities, Minnesota
Modulation of Incretins as a Novel Treatment for Alzheimer's Disease
Investigator-Initiated Research Grant – $200,000 over three years

Mississippi

Vijay Rangachari, Ph.D.
The University of Southern Mississippi
Hattiesburg, Mississippi
Understanding the Role of Granulin in for Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Jun Ming Wang, Ph.D.
University of Mississippi Medical Center
Jackson, Mississippi
ER-Isoform Specific Estrogen Therapy in ApoE/AD Mice
Investigator-Initiated Research Grant – $200,000 over three years

Missouri

Margo-Lea Hurwicz, Ph.D.
University of Missouri
St. Louis, Missouri
Developing a Culturally Appropriate Measure of Alzheimer's Knowledge
Investigator-Initiated Research Grant – $200,000 over three years

Vitaly Klyachko, Ph.D.
Washington University in St. Louis
St. Louis, Missouri
Dissecting the Mechanisms of Synaptic Dysfunction in Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Montana

John J. Lawrence, Ph.D.
The University of Montana
Missoula, Montana
Acetylcholine and Somatostatin Interactions in Alzheimer's Disease Models
New Investigator Research Grant – $80,000 over two years

New Mexico

Eva Y. Chi, Ph.D.
University of New Mexico
Albuquerque, New Mexico
Lipid Membrane Mediated Tau Aggregation and Toxicity
New Investigator Research Grant – $80,000 over two years

New York

Alejandra Alonso, Ph.D.
College of Staten Island/CUNY jointly with Research Foundation/CUNY
Staten Island, New York
Tau-Induced Neurodegeneration
Investigator-Initiated Research Grant – $200,000 over three years

Ottavio Arancio, M.D., Ph.D.
Columbia University
New York, New York
Dysregulation of Histone Acetylation in Alzheimer's Disease
Investigator-Initiated Research Grant – $200,000 over three years

Allal Boutajangout, Ph.D.
New York University School of Medicine
Manhattan, New York
Influence of Presenilin Mutation on Tau Pathology
Mentored New Investigator Research Grant to Promote Diversity – $120,000 over three years

Yu-Ping Chang, Ph.D.
The Research Foundation of State University of New York
Buffalo, New York
Medication Use for Dementia in Chinese-American Families
New Investigator Research Grant – $80,000 over two years

Jimmy Choi, Psy.D.
The Research Foundation for Mental Hygiene at New York State Psychiatric Institute,
Columbia University
New York, New York
Motivational Cognitive Rehabilitation in Mild Cognitive Impairment
Investigator-Initiated Research Grant – $200,000 over three years

Luciano D'Adamio, M.D.
Albert Einstein College of Medicine of Yeshiva University
Bronx, New York
BRI2 and AD Therapy
Investigator-Initiated Research Grant – $200,000 over two years

Mauro Fa, Ph.D.
Columbia University Medical Center
New York, New York
LTP and Memory Impairment by Prolonged Exposure to Picomolar Beta-Amyloid
New Investigator Research Grant – $80,000 over two years

Hiroyasu Furukawa, Ph.D.
Cold Spring Harbor Laboratory
Cold Spring Harbor, New York
Structural Insight into Allosteric Inhibition of NMDA Receptors
New Investigator Research Grant – $80,000 over two years

Lidia Glodzik, M.D., Ph.D.
New York University School of Medicine
New York, New York
Perfusion Abnormalities in Healthy Subjects at Risk for Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Jin Ryoun Kim, Ph.D.
Polytechnic Institute of NYU
Brooklyn, New York
Design of a Molecular Probe for Rapid In Situ Amyloid Aggregation Detection
New Investigator Research Grant – $80,000 over two years

Elena Leznik, Ph.D.
Columbia University Medical Center
New York, New York
Role of SUMOylation in Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Li Liu, Ph.D.
Columbia University Medical Center
New York, New York
Chronic Cerebral Hypoperfusion and Alzheimer's Disease Pathogenesis
New Investigator Research Grant – $80,000 over two years

Sharon E. McKenzie, Ph.D.
State University of New York Downstate Medical Center
Brooklyn, New York
Cognitive Health and Perceived Needs Among Minority Older Adults
Mentored New Investigator Research Grant to Promote Diversity – $120,000 over three years

Lisa Mosconi, Ph.D.
New York University School of Medicine
New York, New York
Maternal History of Alzheimer Predisposes Children to Brain Hypometabolism
Investigator-Initiated Research Grant – $200,000 over three years

Kenneth Norman, Ph.D.
Albany Medical College
Albany, New York
Functional Analysis of SEL-12/Presenilin on Calcium Release in C. Elegans
New Investigator Research Grant – $80,000 over two years

Joanna Pankiewicz, M.D., Ph.D.
New York University School of Medicine
New York, New York
Passive Immunization for Prion Infections
New Investigator Research Grant – $80,000 over two years

Nikolaos Scarmeas, M.D.
Columbia University
New York, New York
Mediterranean Diet and AD in the Mediterranean Region
Investigator-Initiated Research Grant – $200,000 over three years

William E. Van Nostrand, Ph.D.
The Research Foundation of SUNY- SUNY at Stony Brook
Stony Brook, New York
Molecular Seeding of Cerebral Amyloid Angiopathy in Novel Transgenic Mice
Investigator-Initiated Research Grant – $200,000 over three years

North Carolina

Linda L. Buettner, Ph.D.
The University of North Carolina
Greensboro, North Carolina
Mentally Stimulating Activities (MSAs) to Treat Apathy in Early Stage AD
Investigator-Initiated Research Grant – $200,000 over three years

Donna M. Wilcock, Ph.D.
Duke University Medical Center
Durham, North Carolina
A Study to Validate Tau as a Therapeutic Target for Alzheimer's Disease
New Investigator Research Grant – $80,000 over two years

Ohio

Hyoung-Gon Lee, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Effect and Mechanism of Cell Cycle Re-Entry in Neurodegeneration
New Investigator Research Grant – $80,000 over two years

Mark A. Smith, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Xanthine Oxidase in AD: Mechanistic and Therapeutic Opportunities
Investigator-Initiated Research Grant – $200,000 over three years

Oregon

P. Hemachandra Reddy, Ph.D.
Oregon Health & Science University
Beaverton, Oregon
Neuroprotection and Alzheimer's Disease
Investigator-Initiated Research Grant – $200,000 over three years

Rhode Island

Sean Deoni, Ph.D.
Brown University
Providence, Rhode Island
Investigation of Myelin Loss Associated with Alzheimer's Dementia
New Investigator Research Grant – $80,000 over two years

Texas

Valarie Fleming, Ph.D.
Texas State University
San Marcos, Texas
Early Detection of Mild Cognitive Impairment: Cognitive-Communicative Change
New Investigator Research Grant to Promote Diversity – $80,000 over two years

Denise C. Park, Ph.D.
The University of Texas at Dallas
Dallas, Texas
Amyloid Deposition, Aging, and Neurocognitive Function
Investigator-Initiated Research Grant – $200,000 over three years

Utah

Richard D. King, M.D., Ph.D.
University of Utah
Salt Lake City, Utah
Complexity Measures of the Cerebral Cortex in Neurodegenerative Disease
New Investigator Research Grant to Promote Diversity – $80,000 over two years

Wisconsin

Barbara B. Bendlin, Ph.D.
University of Wisconsin-Madison
Madison, Wisconsin
White Matter Alterations in Middle-Aged Adults at Risk for Alzheimer's
New Investigator Research Grant – $80,000 over two years

Michele L. Ries, Ph.D.
University of Wisconsin-Madison
Madison, Wisconsin
Multimodal Neuroimaging of Apathy in Amnestic Mild Cognitive Impairment
New Investigator Research Grant – $80,000 over two years

Marie Savundranayam, Ph.D.
University of Wisconsin-Milwaukee
Milwaukee, Wisconsin
Caregiver Communication Strategies: Implications for Relational Outcomes
New Investigator Research Grant – $80,000 over two years

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