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Funded Studies 2005-2013


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Funded Studies: 2011


ARGENTINA

Eduardo M. Castaño, M.D.
Leloir Institute Foundation
Buenos Aires, Argentina 
Neuronal Vulnerability to Amyloid Peptides: From Drosophila to Human Brain
Investigator-Initiated Research Grant — $200,000 over three years

AUSTRALIA

Paul A. Adlard, Ph.D.
Mental Health Research Institute
Parkville, Australia
Metals and Neurofibrillary Tangles: A Novel Therapeutic Target
New Investigator Research Grant — $96,000 over two years

CHINA

Ling-Qiang Zhu, Ph.D., M.D.
Huazhong University of Science and Technology
Wuhan, China
Role of EphB2 Signal in Tau Pathology in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

ISRAEL

Dan Frenkel, Ph.D.
Tel Aviv University
Tel Aviv, Israel
The Role of Specific Gamma Secretase Pathways in Microglia Activation
New Investigator Research Grant — $99,200 over two years

Ramit Ravona-Springer, M.D.
Sheba Medical Center
Ramat Gan, Israel
Dietary Factors, Inflammation, and Cognitive Decline in Diabetic Elderly
New Investigator Research Grant — $100,000 over two years

ITALY

Olga Bruno, Ph.D.
University of Genoa
Genoa, Italy 
PDE4D Selective Inhibitors for the Treatment of Memory Impairment
Investigator-Initiated Research Grant — $200,000 over three years

Maria Cotelli, Ph.D.
Scientific Institute of Cure and Hospitalization
Brescia, Italy
Alzheimer's Disease: A New Approach to Cognitive Neurorehabilitation
New Investigator Research Grant — $100,000 over two years

Marcello D'Amelio, Ph.D.
IRCCS Santa Lucia Foundation 
Rome, Italy
Preventing and Monitoring Onset of Synaptic Degeneration in Early Alzheimer's Disease
New Investigator Research Grant — $99,400 over two years

Elisa Mura, Ph.D.
University of Pavia
Pavia, Italy
Mechanisms of the Neuromodulatory Action of Beta-Amyloid
New Investigator Research Grant — $99,000 over two years

Giacomina Rossi, Ph.D.
Foundation Carlo Besta Neurological Institute 
Milan, Italy
The Role of Tau in Chromosome Stability and Its Link to Neurodegeneration
New Investigator Research Grant — $99,935 over two years

MEXICO

Fernando Pena, Ph.D.
Neurobiology Institute at the National Autonomous University of Mexico
Queretaro, Mexico
Disruption of Interneuronal Networks by Beta-Amyloid
New Investigator Research Grant — $100,000 over two years

UNITED KINGDOM

David J. Llewellyn, Ph.D.
Peninsula Medical School
Universities of Exeter and Plymouth
Exeter, United Kingdom
Vitamin D and the Risk of Dementia in the Cardiovascular Health Study
New Investigator Research Grant — $99,662 over two years

UNITED STATES

California

David H. Cribbs, Ph.D.
University of California—Irvine
Irvine, California
Hypertension, Cerebral Amyloid Angiopathy and Neuroinflammation
Investigator-Initiated Research Grant — $200,000 over three years

Geoffrey A. Kerchner, M.D., Ph.D.
Stanford University
Stanford, California
Hippocampal StriatalAnatomy in Mild Cognitive Impairment: A 7T MRI Study
New Investigator Research Grant — $100,000 over two years

Tomohiro Nakamura, Ph.D.     
Sanford-Burnham Medical Research Institute
La Jolla, California
Role of S-Nitrosylation in Alzheimer's Disease
New Investigator Research Grant — $97,443 over two years

Robert A. Rissman, Ph.D.
University of California—San Diego 
La Jolla, California
CRF Receptor Antagonism in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Susanna Rosi, Ph.D.
University of California—San Francisco
San Francisco, California
Restoring Synaptic Plasticity in a Transgenic Rat Model of Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Sophie Sokolow, Ph.D.
University of California—Los Angeles 
Los Angeles, California
Biochemical and Functional Analyses of the Na+/Ca2+ (NCX) Exchanger in Alzheimer's Disease Pathology
New Investigator Research Grant — $100,000 over two years

Brian Wiltgen, Ph.D.
The Regents of the University of California, University of California
Davis, California
The Role of Synaptic Plasticity in the Development of Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Connecticut

Min Wang, Ph.D.
Yale University
New Haven, Connecticut
Nicotinic Alpha7-NMDA Receptor Interactions in the Aged Nonhuman Primate
New Investigator Research Grant to Promote Diversity — $100,000 over two years

Georgia

Yvonne D. Eaves, Ph.D.
Kennesaw State University
Georgia
Caregiving Transitions in Alzheimer's Disease for Rural African-Americans
The Senator Mark Hatfield Award for Clinical Research in Alzheimer's Disease — $200,000 over three years

Illinois

David X. Marquez, Ph.D.
University of Illinois at Chicago 
Chicago, Illinois
BAILA-C: Bypassing Alzheimer's, Increasing Latinos' Activity and Cognition
New Investigator Research Grant to Promote Diversity — $99,223 over two years

Raksha Mudar, Ph.D.
The Board of Trustees of the University of Illinois at Urbana-Champaign
Champaign, Illinois
Neural Markers of Subjective Cognitive Impairment
New Investigator Research Grant — $100,000 over two years

Gustavo F. Pigino, Ph.D.
University of Illinois at Chicago
Chicago, Illinois
Mechanism Underlying Oligomeric Abeta Induced-Axonal Transport Dysfunction
New Investigator Research Grant to Promote Diversity — $100,000 over two years

Sangram S. Sisodia, Ph.D.
University of Chicago 
Chicago, Illinois
Functional Analysis of Nicastrin
Investigator-Initiated Research Grant — $200,000 over three years

Neil Smalheiser, M.D., Ph.D.
University of Illinois at Chicago 
Chicago, Illinois
Plasma Small RNAs as Biomarkers for Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Mehul A. Trivedi, Ph.D.
Rush University Medical Center
Chicago, Illinois
Neural Correlates of Cognitive Efficiency in Individuals at Risk for Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Indiana

Debomoy K. Lahiri, Ph.D.
Indiana University
Indianapolis, Indiana
Novel Regulation of APP and Beta-Secretase (BACE) in Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Kentucky

Mubeen Ansari, Ph.D.
University of Kentucky Research Foundation
Lexington, Kentucky
The Complex Role of NADPH-Oxidase (NOX) in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Massachusetts

Brian J. Bacskai, Ph.D.
Massachusetts General Hospital
Charlestown, Massachusetts
Understanding the Selective Vulnerability of Neurons in Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Raymond J. Kelleher, M.D., Ph.D.
Massachusetts General Hospital
Boston, Massachusetts
Developing Knock-In Mouse Models of Loss of Presenilin Function in Familial Alzheimer's Disease (FAD)
Investigator-Initiated Research Grant — $200,000 over three years

Diane F. Mahoney, Ph.D.
MGH Institute of Health Professions 
Boston, Massachusetts
Context Aware Computing with Motivational Counseling to Enable Dressing
Everyday Technologies for Alzheimer's Care — $180,000 over two years

Jorge Sepulcre, M.D., Ph.D.
Massachusetts General Hospital
Boston, Massachusetts
Brain Hubs of Amyloid Deposition in Preclinical Stages of Dopamine Active Transporter (DAT)
New Investigator Research Grant — $99,994 over two years

Richard Sherva, Ph.D., M.P.H. 
Boston University
Boston, Massachusetts
Genetics of Rate of Cognitive Decline in a Clinical Trial of Alzheimer's Disease
New Investigator Research Grant — $99,072 over two years

Jacob Sloane, M.D., Ph.D.
Beth Israel Deaconess Medical Center 
Boston, Massachusetts
Double Stranded RNA Receptor Function in Neurofibrillary Tangle Formation
New Investigator Research Grant — $100,000 over two years

Minnesota

Prashanthi Vemuri, Ph.D.
Mayo Clinic
Rochester, Minnesota
Functional Reorganization of the Brain: Response to Alzheimer's Pathology?
New Investigator Research Grant — $100,000 over two years

Missouri

Randall J. Bateman, M.D.
Washington University in St. Louis
St. Louis, Missouri
A Blood Isotope Labeled Amyloid-Beta Test for Alzheimer's Disease
Zenith Fellows Award — $450,000 over three years

Carlos Cruchaga, Ph.D.
Washington University in St. Louis
St. Louis, Missouri
Exome Sequencing of Late-Onset Alzheimer's Disease Families
New Investigator Research Grant — $99,677 over two years

William Z. Suo, M.D.
Midwest Biomedical Research Foundation 
Kansas City, Missouri
Fighting Against Alzheimer's Selective Cholinergic Neurodegeneration
Novel Pharmacological Strategies to Prevent Alzheimer's Disease — $399,900 over three years

Nebraska

Jyothi Arikkath, Ph.D.
University of Nebraska Medical Center
Omaha, Nebraska
Cooperation of d-Catenin and Presenilin in the Synaptic Pathology of Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Stephen J. Bonasera, M.D., Ph.D.
University of Nebraska
Omaha, Nebraska
Multimodal Monitoring of Functional Status in Moderate Alzheimer's Disease
Everyday Technologies for Alzheimer's Care — $200,000 over three years

New York

John F. Crary, M.D., Ph.D.
Columbia University Medical Center 
New York, New York
MicroRNA Regulation of MAPT in Alzheimer's Disease, Limbic Type
New Investigator Research Grant — $100,000 over two years

Luciano D'Adamio, M.D.
Albert Einstein College of Medicine of Yeshiva University 
Bronx, New York
Genetic and Biochemical Analysis of Synaptic Dysfunction in Dementia
Zenith Fellows Award — $450,000 over three years

Gilbert Di Paolo, Ph.D.
Columbia University Medical Center 
New York, New York
Role of Phospholipase D1 in Alzheimer's Disease Pathogenesis
Investigator-Initiated Research Grant — $200,000 over three years

Mauro Fa, Ph.D.
Columbia University Medical Center 
New York, New York
Memory Impairment by Soluble Oligomeric Tau
Investigator-Initiated Research Grant — $200,000 over three years

Yitshak I. Francis, Ph.D.
Columbia University Medical Center 
New York City, New York
The Involvement of Histone Acetyl-Transferases (HAT) in Alzheimer's Disease
New Investigator Research Grant — $99,999 over two years

Anastasios Georgakopoulos, Ph.D.
Mount Sinai School of Medicine 
New York, New York
Mechanisms of Neuroprotection by Presenilin 1
Investigator-Initiated Research Grant — $200,000 over three years

Jorge A. Ghiso, Ph.D.
New York University School of Medicine 
New York, New York
Abeta Catabolism and Its Impact in Alzheimer's Disease Pathogenesis
Investigator-Initiated Research Grant — $200,000 over three years

Fenghua Hu, Ph.D.
Cornell University 
Ithaca, New York
Regulation of Microglia Responses to A-Beta by Progranulin
New Investigator Research Grant — $100,000 over two years

Costantino Iadecola, M.D.
Joan & Sanford I. Weill Medical College of Cornell University 
New York, New York
Interaction Between Hypertension and Alzheimer's Disease
Zenith Fellows Award — $450,000 over three years

Gurjinder Kaur, Ph.D.
The Nathan S. Kline Institute for Psychiatric Research 
Orangeburg, New York
Intracellular Oligomeric Abeta and Endosomal Pathology in APPE693Q Mice
Investigator-Initiated Research Grant — $200,000 over three years

Dimitris N. Kiosses, Ph.D.
Joan & Sanford I. Weill Medical College of Cornell University
New York, New York
Home-Delivered Intervention for Depression in Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Jennifer J. Manly, Ph.D.
Columbia University Medical Center 
New York, New York
Offspring of Ethnically Diverse People With and Without Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Andrew Munkasci, Ph.D.
Columbia University Medical Center 
New York, New York
HDAC Inhibition: Treating Dementia Through Cholesterol Transport and CLU
New Investigator Research Grant — $99,990 over two years

Ricardo S. Osorio, M.D.
New York University School of Medicine
New York, New York
Is Sleep Disordered Breathing in Normal Aging a Risk Factor for Alzheimer's Disease?
New Investigator Research Grant — $99,778 over two years

Andrew Teich, M.D., Ph.D.
Columbia University Medical Center 
New York, New York
Beta-Amyloid 42 Positively Regulates Alpha7-Cholinergic Receptors
New Investigator Research Grant — $100,000 over two years

Guang Yang, Ph.D.
New York University School of Medicine
New York, New York
Synaptic Pathology Underlying Memory Loss in a Mouse Model of Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Wai Haung Yu, Ph.D.
Columbia University Medical Center 
New York, New York
Regionally Differential Autophagic Protein Degradation Expression in Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Molly E. Zimmerman, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Bronx, New York
Chronic Pain and Cognitive Dysfunction in Older Adults
New Investigator Research Grant — $100,000 over two years

Ohio

Kiran Bhaskar, Ph.D.
Cleveland Clinic Foundation 
Cleveland, Ohio
Role of Tau Protein in the Inflammation-Mediated Neurotoxicity
New Investigator Research Grant — $100,000 over two years

Bruce T. Lamb, Ph.D.
Cleveland Clinic
Cleveland, Ohio
The Role of Mononuclear Phagocytes in Tauopathies
Multi-Centered Project Grant-Component Project 1 — $340,000 over three years

Sanjay W. Pimplikar, Ph.D.
Cleveland Clinic
Cleveland, Ohio
Inflammation and Microglial Activation in AICD Transgenic Mice
2011 Multi-Centered Project Grant-Component Project 2 — $240,000 over three years

Richard M. Ransohoff, M.D.
Cleveland Clinic
Cleveland, Ohio
Genetic Tagging of Mononuclear Phagocytes in Alzheimer's Mouse Models
2011 Multi-Centered Project Grant-Component Project 3 — $240,000 over three years

Gary Landreth, Ph.D.
Case Western Reserve University
Cleveland, Ohio 
Mechanisms of RXR-Stimulated Reversal of Amyloid-Induced Phenotypes
Zenith Fellows Award — $450,000 over three years

Hyoung-gon Lee, Ph.D.
Case Western Reserve University
Cleveland, Ohio
Pathogenic Mechanism of Neuronal Cell Cycle Re-Entry in Alzheimer's Disease
Investigator-Initiated Research Grant — $200,000 over three years

Xinglong Wang, Ph.D.
Case Western Reserve University School of Medicine
Cleveland, Ohio
Presenilin 1 as a Regulator of Mitochondrial Dynamics
New Investigator Research Grant — $100,000 over two years

Dan Wesson, Ph.D.
Case Western Reserve University
Cleveland, Ohio
The Biological Basis of Phenotypic Diversity of Microglia in AD
2011 Multi-Centered Project Grant-Component Project 4 — $240,000 over three years

Pennsylvania

Jeannie Chin, Ph.D.
Thomas Jefferson University
Philadelphia, Pennsylvania
Dysregulation of Corticothalamic Circuitry in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Tennessee

Francesca-Fang Liao, Ph.D.
University of Tennessee Health Science Center 
Memphis, Tennessee
Novel Regulation of BACE1 by Nitrosative and Metabolic Stresses
Investigator-Initiated Research Grant — $200,000 over three years

Texas

Anil K. Mantha, Ph.D.
University of Texas Medical Branch at Galveston 
Galveston, Texas
APE1/Ref-1's Dual Functions Countering Beta Amyloid Induced Genotoxicity
New Investigator Research Grant — $99,990 over two years

Gang Yu, Ph.D.
University of Texas Southwestern Medical Center 
Dallas, Texas
Models, Imaging and Drugs for TDP-43 Pathobiology
Investigator-Initiated Research Grant — $200,000 over three years

Utah

John S.K. Kauwe, Ph.D.
Brigham Young University 
Provo, Utah
Genetic and Environmental Influences on Rate of Progression of Alzheimer's Disease
Mentored New Investigator Research Grant to Promote Diversity — $149,831 over three years

Virginia

Rebecca G. Logsdon, Ph.D.
University of Washington 
Seattle, Washington
Two Interventions for Early Stage Dementia: A Comparative Efficacy Trial
Non-Pharmacological Strategies to Ameliorate Symptoms of Alzheimer's Disease — $399,990 over three years

Washington DC

Giuseppe Astarita, D.Sc.
Georgetown University School of Medicine
Washington DC
Lipidomic Biosignature in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

West Virginia

Justin Legleiter, Ph.D.
West Virginia University Foundation 
Morgantown, West Virginia
Mechanisms and Consequences of Beta-Amyloid Binding to Cellular Surfaces
New Investigator Research Grant — $99,592 over two years

Wisconsin

Nashaat Gerges, Ph.D.
Medical College of Wisconsin 
Milwaukee, Wisconsin
Role of Retinoic Acid in Alzheimer's Disease
New Investigator Research Grant — $100,000 over two years

Joseph Goveas, M.D.
Medical College of Wisconsin 
Milwaukee, Wisconsin
Multimodal Imaging in Depressed Adults at Risk for Alzheimer's Disease
New Investigator Research Grant — $99,994 over two years

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