Get Involved

Progress in Alzheimer's and dementia research depends on clinical studies and eligible participants are needed to move this vital research forward.


COVID-19 Update

U.S. POINTER study leadership has been closely monitoring the novel coronavirus (COVID-19) situation. Based on guidance from the Centers for Disease Control and local authorities, we have determined that it is safe to restart in-person research activities.

Please know that we will continue to monitor the situation and will take recommended precautions to protect the health and safety of U.S. POINTER participants and staff.

Key Eligibility for U.S. POINTER

  • People between the ages of 60 and 79
  • People who are not regular exercisers (generally less than 3 times per week)
  • People who may have other risks for memory loss in the future such as family history of memory problems or slightly high blood pressure, cholesterol or blood sugar.
  • Live within an area where the study is being conducted
  • Additional criteria evaluated at screening

Not eligible for this study? Learn about other Clinical Trials.

Study Locations


Wake Forest School of Medicine

Winston-Salem, North Carolina
Co-Principal Investigators:
Jeff Williamson, M.D. and Maryjo Cleveland, M.D.
Recruitment information
Phone: 1.833.361.7591
Email: pointerstudy@wakehealth.edu


UC Davis School of Medicine


Sacramento, California
Co-Principal Investigators:
Rachel Whitmer, Ph.D. and Sarah Farias, Ph.D.
Recruitment information
Phone: 1.916.734.0121
Email: pointerstudy@ucdavis.edu


Rush University Medical Center

Chicago, Illinois
Principal Investigator:
Christy Tangney, Ph.D.
Recruitment information
Phone: 1.708.660.6463
Email: pointer@rush.edu

 


Advocate Health Care

Chicago, Illinois
Principal Investigator:
Darren Gitelman
Recruitment information
Phone: 1.847.720.6467
Email: lgh-uspointer@advocatehealth.com


Baylor College of Medicine

Houston, Texas
Co-Principal Investigators:
Valory Pavlik and Melissa Yu
Recruitment information
Phone: 1.713.798.5452
Email: ADPrevention@bcm.edu

 


Add-On Studies

U.S. POINTER add-on studies look deeper into the science of the main study. The neuroimaging ancillary study is the first large-scale investigation of how lifestyle interventions affect biological changes in the brain associated with Alzheimer's and dementia. The sleep ancillary study will examine whether changes in sleep predict changes in overall cognitive function or in specific areas, such as memory.

The U.S. POINTER Neuroimaging Ancillary Study
The U.S. POINTER-zzz Sleep Study


Other Clinical Trial Opportunities

Contributing to progress in Alzheimer’s research is a highly valuable contribution to a better future for all. If you are not a potential fit for U.S. POINTER or do not live near a U.S. POINTER study site, there are many other important clinical trials underway that need participants.

Learn about studies that are currently recruiting participants by visiting alz.org/TrialMatch and completing a TrialMatch profile online or call 1.800.272.3900 (press 1 for clinical trials). Completing a TrialMatch profile does not commit you to participating in a study.

Get U.S. POINTER Information

Whether you are a researcher or potential participant, use this contact information to receive answers to your questions regarding U.S. POINTER.

Email: POINTERinfo@alz.org
Phone: 800.272.3900



Get Involved
Who We Are
Resources
Contact