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2018 Pilot Awards for Global Brain Health Leaders (GBHI)

Cognitive Behavioral Therapy of Insomnia in Mild Cognitive Impairment

Elissaios Karageorgiou, MD, Ph.D.
University of California
San Francisco, CA - United States

More than 50% of individuals with dementia experience sleep disruptions or poor sleep patterns that precede cognitive impairment by several years. Although a technique called Cognitive Behavioral Therapy of insomnia (CBTi) is known to be the most effective treatment of insomnia, its potential benefit has never been evaluated in individuals with dementia. Dr. Karageorgiou plans to evaluate this intervention in people with mild cognitive impairment (MCI) or mild dementia and evaluate sleep quality 3 months and 1-year after treatment. Dr. Karageorgiou suggests that this intervention could help improve sleep of the participants. He will also evaluate impact on cognition. If successful, these study results could be used to justify larger studies that evaluate sleep-related interventions including CBTi therapy.

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