Triple Your Impact This Holiday Season
Triple Your Impact This Holiday Season
Celebrate the holidays with a year-end gift that can go 3x as far to help provide care and support to the millions affected by Alzheimer's disease, and to advance critical research. But please hurry — this 3x Match Challenge ends soon.
Donate NowRide to End ALZ® South Carolina is a 3-Day Cross-State Ride Raising Funds for Alzheimer’s Research, Care and Support through the Alzheimer’s Association
On July 11-13, 2025, cyclists will gather at the CCNB Amphitheatre at Simpsonville’s Heritage Park for the starting line of the Alzheimer’s Association® Ride to End ALZ South Carolina, presented by the David Moore Foundation. Cyclists from the event are a familiar sight on local roadways as they train their minds and bodies for the annual ride across South Carolina in the summer heat. The ride will begin in Simpsonville and wind its way to Mt. Pleasant, with overnight stops in Newberry and Orangeburg.
“As our riders get ready to pedal across the state, most of them will be doing so in honor or in memory of someone who has had Alzheimer's or another dementia. They ride with the hope and belief that effective treatments — and ultimately a cure — are within sight,” said Jerry Chapman, Director of Ride to End ALZ South Carolina. “The Alzheimer’s Association is leading that fight, both globally and right here in our community.”
The 2025 ride will have more participants than ever before, with 425 cyclists in the group ride, plus over 30 virtual participants. Despite remarkable growth, Ride to End ALZ South Carolina continues to offer a well-supported cross-state bicycle ride providing meals, luggage transportation and medical and mechanical assistance throughout the route. Over the course of the three days, the cyclists share stories and laughs, welcoming new riders into the camaraderie of a passionate community.
The event is also supported by over 100 enthusiastic volunteers and generous sponsors, many of whom pour in as much time and sweat as the cyclists themselves. Whether by helping with registration, assisting with rest stops, loading luggage, serving food or cheering on the cyclists, volunteers make the complex logistics of the ride run smoothly.

This homegrown event started in 2009 with just 20 riders raising $16,000. It has grown steadily each year, thanks to dedicated volunteers and word of mouth among riders. Now in its seventeenth year, Ride to End ALZ South Carolina has already raised over $922,000 toward its $1.5 million goal. Since its inception, the ride has raised over $8.5 million to support the work of the Alzheimer’s Association.
Funds raised by Ride to End ALZ South Carolina will continue to accelerate the Association’s research efforts to discover methods of treatment and prevention for Alzheimer's and all dementia — while also maximizing care and support for all facing the disease through local support services, education programs and a free 24-hour Helpline.
Two group ride options are available for 2025: The Grand Tour (257 miles) and a new Half Tour (136 miles). While the group ride is limited to road cyclists, Ride to End ALZ South Carolina also offers a virtual challenge option that is open to casual bike riders, mountain bikers and spin enthusiasts. Registration for the virtual challenge is free and will remain open through the end of July. To register, donate, or view route details, visit alz.org/ridesc.

Beyond the funds raised and the physical challenge itself, Ride to End ALZ South Carolina raises important awareness of Alzheimer’s and all dementia in each community that it touches.
“We have more hope than ever before,” said Chapman. “There are now FDA-approved treatments that can slow disease progression for people in the early stages of Alzheimer's, making a timely diagnosis critically important. The Alzheimer’s Association urges anyone noticing changes in thinking or memory to be proactive in discussing problems with a doctor.”
To learn more about the Alzheimer’s Association or get support for facing any type of dementia, visit alz.org/sc or call the Association’s 24-Hour Helpline at 800.272.3900.
About the Alzheimer’s Association:
The Alzheimer's Association leads the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer's and all other dementia®.