Dr. Lamb received his bachelor’s degree from Swarthmore College and his Ph.D. from the University of Pennsylvania prior to a post-doctoral fellowship at Johns Hopkins University. In 1996, Dr. Lamb was recruited to Case Western Reserve University, where he rose from assistant to associate professor. 

He joined the Cleveland Clinic in 2005. In 2015, Dr. Lamb joined the Indiana University School of Medicine as director of the Stark Neurosciences Research Institute.

Dr. Lamb’s laboratory works on the basic science of Alzheimer’s disease, with a focus on: 1) genetic modifiers identified from mouse and human studies; 2) microglia and neuronal-microglial communication in the development and progression of Alzheimer’s pathologies; and 3) traumatic brain injury as an environmental modifier for the development of Alzheimer’s pathologies.

In addition, Dr. Lamb is actively involved in advocacy for increased research funding for the disease.