The Sex and Gender in Alzheimer's (SAGA) request for applications aims to support scientific investigation into the contributions of sex-related biological, genetic and lifestyle to the pathophysiology of Alzheimer’s and related dementias.
Potential themes may include but not be limited to investigations that:
- Studies to investigate biological sex differences in aging and AD, including link of hormone, telomeres and other aging-related factors
- Studies of genetic links with APOEe4, X chromosome and other genes, including biological mechanism(s) of action, implications for disease pathogenesis
- Understanding sexual dimorphism in brain function, as it relates to vulnerability for AD and related dementias
- Investigating links between hormone levels (i.e. perimenopause) and energy metabolisms (i.e. shift from glucose to ketone energy usage) for disease pathogenesis
- Investigating the biological sex contributions to brain networks, pathology and link to clinical phenotypes of AD and related dementias
- Understanding various lifestyle factors (i.e. stress, vascular and metabolic contributions, sleep, depression) impact neurobiological context on vulnerability for AD and related dementias
- Investigating stress response differences between male/ female and impact on disease vulnerability as well as ways to ameliorate stress-related impact
CLOSED: New Investigator Research Grant (NIRG)
Funds the next generation of promising scientists who have earned their doctoral degrees within the last 10 years.
CLOSED: New Investigator Research Grant to Promote Diversity (NIRGD)
Funds new investigators from diverse backgrounds with intent to support early career development that will lay groundwork for future research grants.
CLOSED: Mentored New Investigator Research Grant to Promote Diversity (MNIRGD)
Funds mentored research conducted by underrepresented researchers who have earned their doctoral degrees within the last 10 years.
CLOSED: Part the Cloud Request for Applications (RFA): Translational Research Funding for Alzheimer’s Disease – PCTR:
May – November 2015
Program Announcement (3 pages)
Program Announcement (4 pages)
How to apply for a grant
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For more information: Contact firstname.lastname@example.org or call 312.335.5747.
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